I. Intangiriro
Mugukurikirana uburyo bwiza kandi burambye bwo kwita ku ruhu, abaguzi bahinduye ibintu karemano nkibisubizo byububiko. Inganda zita ku ruhu zabonye ihinduka rikomeye ku bicuruzwa karemano, bitewe n’abaguzi biyongera ku mahitamo meza, yangiza ibidukikije atanga umusaruro ushimishije.Phloretinni kimwe mubyo bibandaho kubicuruzwa byuruhu.
II. Phloretin ni iki?
A. Sobanura kandi usobanure inkomoko ya Phloretin
Phloretin, ibinyabuzima byitwa bioactive polifenolique, biva mubishishwa hamwe na pome ya pome, amapera, n'inzabibu. Nibintu byingenzi muri sisitemu yo kurinda ibimera, kubarinda imihangayiko itandukanye nkimirasire yangiza ya UV, virusi, na okiside. Imiterere ya molekulire igizwe nimpeta eshatu, Phloretin ifite ubushobozi budasanzwe bwa antioxydeant hamwe nubushobozi bwa bioactive butuma iba ingirakamaro mubicuruzwa bivura uruhu.
B. Inkomoko yabyo
Phloretin irashobora kuboneka cyane mubishishwa hamwe na pome ya pome, amapera, n'inzabibu, cyane cyane mu mbuto zidahiye. Aya masoko karemano arimo Phloretin nyinshi cyane kubera antioxydants nyinshi, ifasha kurinda imbuto kwangirika kwa okiside mugihe cyeze. Gukuramo Phloretin muri aya masoko bikubiyemo gukusanya no gutunganya neza ibishishwa hamwe na cores kugirango ubone umusaruro mwinshi wuru ruganda rukomeye.
C. Ibyiza nibyiza kuruhu
Phloretin itanga ibintu byinshi byingirakamaro kuruhu, itwarwa na antioxydeant, anti-inflammatory, hamwe ningaruka zabyo. Nka antioxydants ikomeye, Phloretin isiba neza radicals yubusa, ikabuza ingaruka zangiza ingirabuzimafatizo zuruhu no kwirinda gusaza imburagihe. Imiterere ya lipofilique yimvange ituma yinjira byoroshye kuruhu, byongera imbaraga.
Iyo ikoreshwa cyane, Phloretin ifite ubushobozi budasanzwe bwo kubuza umusaruro wa melanin, bigatuma iba umutungo utagereranywa mukuvura hyperpigmentation, ibibara byimyaka, hamwe nuruhu rutaringaniye. Byongeye kandi, Phloretin ifasha kubuza ishyirwaho ryibicuruzwa byanyuma bya glycation (AGEs), bishinzwe gusenyuka kwa kolagen na elastine, biganisha ku ruhu rwuzuye uruhu. Mugabanye imiterere ya AGEs, Phloretin iteza imbere synthesis ya kolagen, igahindura ubworoherane bwuruhu kandi ikagabanya kugaragara kumirongo myiza n'iminkanyari.
Phloretin kandi ifite ibintu byingenzi birwanya anti-inflammatory, bifasha mugutuza no koroshya uruhu. Ifasha kugabanya umutuku no gutwikwa biterwa n’abangiza ibidukikije, nk'umwanda, imirasire ya UV, ndetse no gucika acne. Ningaruka zayo zo guhumuriza, Phloretin yongerera imbaraga uruhu rwumubiri rwuruhu, igatera isura nziza.
Inyungu zuzuye za Phloretin zagaragajwe binyuze mubushakashatsi butandukanye bwa siyansi no mu mavuriro. Ubushakashatsi bwemeje ubushobozi bwabwo mu kugabanya hyperpigmentation, kunoza imiterere yuruhu hamwe nimiterere, no gukangura synthesis. Byongeye kandi, Phloretin yerekanwe kuzamura urumuri rusange, ubusore, nubuzima bwuruhu, bituma iba ingenzi muburyo bwo gukora ibicuruzwa bivura uruhu.
Mu gusoza,Inkomoko ya Phloretin muri pome, amapera, n'inzabibu, hamwe na antioxydeant, anti-inflammatory, hamwe no kumurika, ibishyira mu mwanya w'ingenzi mu guhindura inganda zita ku ruhu. Inkomoko karemano ninyungu zemejwe na siyansi bituma iba ikintu cyashakishijwe mugushakisha uburyo bwiza bwo kuvura uruhu, butera imbere, kandi burambye. Mugukoresha imbaraga za Phloretin, abantu barashobora guhinduka muburyo budasanzwe bwuruhu rwabo, bagaragaza ibara ryinshi kandi rishya.
III. Kuzamuka kwa Phloretin mubuvuzi bwuruhu
A. Amavu n'amavuko ya Phloretin mubicuruzwa bivura uruhu
Phloretin ifite amateka akomeye yo gukoresha mubicuruzwa byuruhu, kuva kera. Inkomoko yacyo irashobora gukomoka kubikorwa gakondo byubuvuzi, aho imico imwe n'imwe yamenyaga ibintu bikomeye bya pome, amapera, nibishishwa byinzabibu. Gukuramo Phloretin muri ayo masoko karemano bikubiyemo gutunganya neza kugirango ubone ibice byinshi. Bitewe niterambere ryakozwe mubushakashatsi nubuhanga, siyanse igezweho yo kuvura uruhu ubu ikoresha imbaraga za Phloretin ninyungu zidasanzwe zuruhu.
B. Impamvu zituma abantu biyongera
Kwiyongera kwa Phloretin mubuvuzi bwuruhu birashobora guterwa nubuhanga bwerekanwe mubuhanga kandi buhindagurika. Nka polifenolike, Phloretin yerekana ubushobozi bukomeye bwa antioxydeant ifasha kurwanya stress ya okiside no kurinda ingirabuzimafatizo zuruhu kubusa. Uyu mutungo ni ingenzi cyane mukurinda gusaza imburagihe, kuko ushyigikira kuramba nubuzima bwingirangingo zuruhu, bikagabanya kugaragara kumirongo myiza n'iminkanyari.
Byongeye kandi, ubushobozi bwa Phloretin bwo kubuza umusaruro wa melanin bituma buba ikintu cyashakishijwe mugukemura ibibazo nka hyperpigmentation, ibibara byimyaka, hamwe nuruhu rutaringaniye. Muguhagarika inzira ya synthesis ya melanin, Phloretin ifasha kuzimya ibibara byijimye bihari kandi ikabuza gushiraho ibishya, bikavamo ibara ryinshi kandi ryinshi.
Byongeye kandi, imiti igabanya ubukana bwa Phloretin igira uruhare mu gukundwa n’ibicuruzwa bivura uruhu. Gutwika nikintu gikunze kugaragara mubihe bitandukanye byuruhu, harimo acne, rosacea, nuruhu rworoshye. Ingaruka nziza ya Phloretin ifasha gutuza uruhu, kugabanya umutuku, no guteza imbere isura nziza.
C. Ingero z'ibicuruzwa birimo Phloretin ku isoko
Isoko ryita kuruhu rifite ibicuruzwa byinshi bishya bikoresha imbaraga za Phloretin. Urugero rumwe rugaragara ni serumu yashizwemo na Phloretin. Iyi serumu ikozwe hamwe na Phloretin nyinshi, iyi serumu itanga antioxydants ikomeye kandi ikamurika uruhu. Ifite akamaro cyane mugukemura hyperpigmentation, imiterere yuruhu itaringaniye, nibimenyetso byo gusaza, bikagaragaza isura nziza kandi yubusore.
Phloretin nayo yinjizwa mumazi, aho imiterere yacyo itanga imbaraga zo kugumana uruhu rwogutunga uruhu, bigatera umubyimba kandi wuzuye. Usibye inyungu zayo zitanga amazi, ayo mazi yinjizwamo Phloretin atanga antioxydeant yirinda ibibazo by’ibidukikije, birinda ibyangizwa n’umwanda, imirasire ya UV, n’ibindi bintu byo hanze.
Kubashaka ubuvuzi bugenewe, hariho Phloretin irimo ikosora ibiboneka irahari. Ibicuruzwa byabugenewe kugirango biveho ibibara byijimye, inenge, na hyperpigmentation ya post-inflammatory, bitewe nubushobozi bwa Phloretin bwo kubuza umusaruro wa melanin. Hamwe nimikoreshereze ihamye, ibyo bikosora birashobora kunoza cyane ubwumvikane nuburinganire bwuruhu.
Mu gusoza, amateka akomeye ya Phloretin, inyungu zemejwe na siyansi, no gukundwa cyane byatumye yinjizwa mu bicuruzwa bitandukanye bivura uruhu. Kuva kuri serumu kugeza kuri moisturizers hamwe no gukosora ibibanza, Phloretin itanga umurongo mugari wo guhindura uruhu ruhindura. Mugukoresha imbaraga zibi bintu karemano, abantu barashobora kugira iterambere ritangaje mumiterere yuruhu rwabo, amaherezo bagahindura inganda zita kuruhu.
IV. Inyungu za Phloretin mubuvuzi bwuruhu
A. Ingaruka za Phloretin kubibazo bitandukanye byuruhu
Phloretin, ifumbire mvaruganda ikomoka kuri pome, amapera, hamwe nudushishwa twinzabibu, yitabiriwe cyane ninganda zita ku ruhu kubera ingaruka zidasanzwe ku mpungenge zitandukanye z’uruhu. Ubushakashatsi bwa siyansi bwerekanye ubushobozi bwabwo bwo kwinjira mu nzitizi y’uruhu no gutanga ingaruka zihinduka kurwego rwa selile.
Imiterere ya Phloretin ituma ibintu byinshi bihindura ubushobozi bwo gukemura ibibazo byinshi byuruhu icyarimwe. Ikora nk'igikoresho gikomeye cyo kurwanya inflammatory, koroshya uruhu rwarakaye no kugabanya umutuku ujyanye nibibazo nka acne, rosacea, hamwe nuruhu rworoshye. Izi ngaruka zo kurwanya inflammatory ziterwa no guhindura cytokine ya por-inflammatory, igira uruhare runini mu kurwanya ubudahangarwa bw'uruhu.
Byongeye kandi, Phloretin ifite imiterere yihariye yo kumurika uruhu bigatuma iba igisubizo cyiza kuri hyperpigmentation, ibibara byimyaka, hamwe nuruhu rutaringaniye. Muguhagarika enzyme ishinzwe synthesis ya melanin, Phloretin igabanya umusaruro mwinshi wa melanin, biganisha kuri pigmentation ikabije. Igihe kirenze, uku kwivanga munzira yumusaruro wa melanin bifasha kuzimya ibibara byijimye bihari kandi bikabuza gushiraho ibishya, bikavamo kurushaho ndetse no kumurika.
B. Ingaruka za Phloretin mukugabanya Hyperpigmentation hamwe nu mwanya wimyaka
Hyperpigmentation hamwe nu mwanya wimyaka ni impungenge zihoraho, cyane cyane kubashaka ubusore kandi busa neza. Ubushobozi bwa Phloretin bwo kubangamira inzira ya synthesis ya melanin bituma iba ikintu gikomeye mugukemura ibyo bibazo byihariye.
Melanin ashinzwe ibara ryuruhu rwacu, umusatsi, namaso. Nyamara, umusaruro mwinshi wa melanin, akenshi uterwa nizuba, ihinduka ryimisemburo, cyangwa gutwika, birashobora gutuma habaho ibibara byijimye hamwe nuruhu rutaringaniye. Phloretin, ibinyujije mu ngaruka zayo kuri tyrosinase, enzyme ikomeye mu musaruro wa melanin, ihagarika iyi nzira ya pigmentation ikabije.
Mu ruhu, kuba Phloretin ihari bibuza ihinduka rya tirozine muri melanine, bikarinda kubaho ibibara byijimye. Byongeye kandi, ifasha gusenya uduce duto twa melanin, koroshya neza imyaka yimyaka no guteza imbere isura imwe. Iyi nzira ibaho gahoro gahoro, bisaba gukoresha buri gihe ibikoreshwa mu kuvura uruhu rwa Phloretin kubisubizo byiza.
C. Ibintu birwanya Antioxydeant ya Phloretin nubushobozi bwayo bwo kwirinda ibyangiza ibidukikije
Imwe mu nyungu zikomeye za Phloretin mukuvura uruhu nigikorwa cyayo gikomeye cya antioxydeant. Antioxydants igira uruhare runini muguhindura radicals yangiza iterwa nimpamvu zituruka hanze nkumwanda, imirasire ya UV, nuburozi bwibidukikije. Izi radicals zubuntu zirashobora kwangiza ingirabuzimafatizo zuruhu, biganisha ku gusaza imburagihe, kwangirika kwa kolagen, hamwe na stress ya okiside.
Ubushobozi bwa antioxydeant ya Phloretin buri mubushobozi bwayo bwo kwikuramo radicals yubusa, itabangamira ingaruka zangiza. Ikora nk'ingabo, irinda ingirangingo z'uruhu guhagarika umutima kandi ikarinda gusenyuka kwa kolagen na elastine, poroteyine zishinzwe gukomera k'uruhu no gukomera.
Byongeye kandi, imiterere yihariye ya Phloretin ituma yinjira neza mubice byuruhu, bigatuma iba umukandida mwiza mugutanga antioxydants irinda igihe kirekire. Imiterere ya lipofilique yemeza ko ishobora kwambuka byoroshye ingirabuzimafatizo ikungahaye kuri lipide, ikongera ibikorwa byayo kurwanya radicals yubuntu no kugabanya ingaruka mbi ziterwa n’ibidukikije ku ruhu.
Mu gusoza, inyungu za Phloretin zinyuranye mu kwita ku ruhu zifitanye isano itaziguye no kurwanya indwara, kumurika, no kurwanya antioxydeant. Mu gukemura ibibazo bitandukanye nka hyperpigmentation, aho imyaka igeze, umutuku, no kwangiza ibidukikije, Phloretin yagaragaye nkibintu bisanzwe bifite ingaruka zihinduka. Ubushobozi bwayo bwo kwinjira mu ruhu, bigira ingaruka kuri synthesis ya melanin, no gutesha agaciro radicals yubuntu itandukanya nkumukinnyi wingenzi muguhindura inganda zita ku ruhu.
V. Ubushakashatsi n'Ubushakashatsi
A. Imbaraga za siyanse zishyigikira imikorere ya Phloretin
Ubushakashatsi bwa siyansi kuri Phloretin bwemeje nta gushidikanya ko bufite akamaro mu guhindura inganda zita ku ruhu. Abashakashatsi bakoze ubushakashatsi bwimbitse ku miterere yihariye n’uburyo bukoreshwa, berekana impamvu iki kintu gisanzwe gikurura abakunzi b’uruhu.
Ubushakashatsi bwerekanye ubushobozi bwa Phloretin bwo kwinjira mu nzitizi y’uruhu no kugera ku bice byimbitse aho ingaruka zabyo zihinduka. Iyi mikorere idasanzwe itandukanya Phloretin nibindi bintu byinshi byita ku ruhu, ikabasha kwishora hamwe ningirangingo zuruhu no gutanga inyungu zayo nyinshi kurwego rwa selile.
Byongeye kandi, ibimenyetso byinshi bigenda byerekana Phloretin nk'umuti ukomeye wo kurwanya inflammatory. Gutwika ni moteri yingenzi yibibazo byuruhu bitandukanye, kuva acne na rosacea kugeza uruhu rworoshye, rukora. Muguhindura cytokine itera inflammatory, Phloretin ifasha gutuza uruhu rwarakaye, kugabanya umutuku, no guteza imbere isura ituje. Ubu bushakashatsi butanga ubumenyi bukomeye bwa siyanse ya Phloretin irwanya inflammatory hamwe nubushobozi bwayo mugukemura ibibazo byuruhu birangwa no gutwika.
B. Igeragezwa rya Clinical: Gupfundura ibisubizo bishingiye ku bimenyetso
Igeragezwa ry’amavuriro ryagize uruhare runini mu kwerekana ubushobozi nyabwo bwa Phloretin mu kwita ku ruhu, bitanga ibisubizo bishingiye ku bimenyetso bishimangira izina ryabyo nkibintu bisanzwe bihindura ibintu. Ubu bushakashatsi bwakozwe mubihe byagenzuwe nabitabiriye amahugurwa, butanga umusingi ukomeye wo gushyigikira imikorere ya Phloretin.
Ibigeragezo byinshi byamavuriro byagaragaje cyane cyane ingaruka za Phloretin kuri hyperpigmentation, ibibara byimyaka, hamwe nuruhu rutaringaniye. Ibisubizo byerekana buri gihe ubushobozi bwa Phloretin bwo guhagarika enzyme ishinzwe synthesis ya melanin, bityo bikagabanya pigmentation ikabije kandi bigatera isura nziza. Abitabiriye amahugurwa bakoresha ibicuruzwa byita ku ruhu rwa Phloretin bavuze ko hari byinshi byahinduye mu kugaragara kw'ibibara byijimye, biganisha ku ruhu rwinshi ndetse ndetse rukaba rwinshi. Ibyavuye mu bushakashatsi birashimangira ibimenyetso bidashidikanywaho byerekana izina rya Phloretin nk'igisubizo cyiza kubibazo bya hyperpigmentation.
Byongeye kandi, ibizamini byo kwa muganga byanasobanuye neza antioxydeant ya Phloretin n'uruhare rwayo mu kurinda uruhu kwangiza ibidukikije. Abitabiriye amahugurwa bakoresheje Phloretin bashingiye ku miterere bagaragaje ko barushijeho guhangana n’uruhu rwo kurwanya umwuka wa okiside uterwa n’umwanda hamwe n’imirasire ya UV. Ubu bushakashatsi bushigikira igitekerezo cyuko Phloretin ikora nkingabo ikomeye, ikarinda gusaza imburagihe, kwangirika kwa kolagen, no kwangiza uruhu rwa okiside.
Mugukurikiza uburyo bukomeye bwa siyansi, ibizamini byamavuriro bitanga ubumenyi bwingirakamaro mubikorwa bya Phloretin kandi bigafasha kwerekana ko byizewe nkumukino uhindura umukino mubikorwa byo kuvura uruhu. Ibisubizo bishingiye ku bimenyetso bigira uruhare mu gukura kw’ubushakashatsi bushyigikira ikoreshwa rya Phloretin mu kuvura uruhu.
Mu gusoza, ubushakashatsi bwa siyansi n’ibigeragezo by’amavuriro byashimangiye izina rya Phloretin nkibintu bisanzwe bihindura inganda zita ku ruhu. Ubushobozi bwa Phloretin bwinjira mu nzitizi y’uruhu, imiterere yabwo yo kurwanya inflammatory, n’ingaruka zabwo mu kugabanya hyperpigmentation no kurinda ibyangiza ibidukikije byasuzumwe neza kandi byemejwe. Ibyavuye mu bushakashatsi ni nk'igitanda cya siyansi gishimangira imikorere ya Phloretin, ikazamura ku isonga mu guhanga udushya two kuvura uruhu.
VI. Ingaruka Zishobora Kuruhande no Kwirinda
A. Gucukumbura Umwirondoro Wumutekano wa Phloretin
Mugusuzuma ubushobozi bwa Phloretin bwo guhindura uruhu, ni ngombwa gusuzuma imiterere yumutekano. Ubushakashatsi bunini bwakozwe kugirango bumve ingaruka zose zishobora kubaho cyangwa ingaruka mbi zijyanye na Phloretin.
Kugeza magingo aya, nta bintu bikomeye byabaye byavuzwe hamwe no gukoresha ibicuruzwa bya Phloretin birimo. Ariko, kimwe nibintu byose byita kuruhu, ibyiyumvo byumuntu birashobora gutandukana. Birasabwa gukora ibizamini mbere yo gusaba byuzuye kugirango byemeze guhuza no kugabanya ingaruka ziterwa no gutungurwa.
B. Gukoresha neza no Kwirinda Phloretin
Kubantu batekereza ibicuruzwa birimo Phloretin, inama zikurikira nuburyo bwo kwirinda:
Ikizamini cya Patch:Koresha agace gato k'ibicuruzwa ahantu h'ubwenge bwuruhu kandi urebe ingaruka mbi zose nko gutukura, guhinda, cyangwa kurakara. Niba hari ingaruka mbi zibaye, hagarika gukoresha ako kanya.
Kurinda izuba:Mugihe Phloretin ishobora gukingira ibidukikije, harimo imirasire ya UV, ni ngombwa kuzuza inyungu zayo hamwe n’izuba ryinshi ryizuba iyo rihuye nizuba. Imirasire y'izuba ntabwo irinda uruhu gusa imirasire yangiza ya UVA na UVB ahubwo inongera imbaraga muri rusange ya Phloretin.
Gusaba neza:Koresha ibicuruzwa birimo Phloretin nkuko byerekanwa nuwabikoze cyangwa inzobere mu kuvura uruhu. Kurikiza inshuro zisabwa, ingano, hamwe na tekinike yo gukoresha kugirango uhindure ibyiza byayo utaremereye uruhu.
Impanuro:Niba ufite ikibazo cyuruhu, allergie, cyangwa impungenge, nibyiza kubaza inzobere mubuzima cyangwa inzobere mu kuvura indwara z’indwara mbere yo kwinjiza Phloretin mubikorwa byawe byo kwita ku ruhu. Barashobora gutanga ibyifuzo byihariye ukurikije ibyo ukeneye n'amateka y'ubuvuzi.
Mu gukurikiza izo ngamba, abantu barashobora gukoresha neza ubushobozi bwa Phloretin mubikorwa byabo byo kwita ku ruhu, bakunguka byinshi mugihe bagabanya ingaruka ziterwa ningaruka mbi.
VII. Umwanzuro
Muri make, Phloretin yagaragaye nkibintu bisanzwe bifite imbaraga zo kuvugurura inganda zita ku ruhu. Binyuze mu bushakashatsi bwa siyansi no mu mavuriro, akamaro kayo mu kurwanya ibibazo bitandukanye byo kwita ku ruhu, kuva hyperpigmentation kugeza gutwika, byemejwe na siyansi.
Byongeye kandi, umutekano wa Phloretin wasuzumwe cyane, nta ngaruka mbi zagaragaye. Nubwo bimeze bityo ariko, ni ngombwa gukora ibizamini bya patch no kubahiriza amabwiriza akoreshwa kugirango tumenye uburambe bushoboka hamwe nibicuruzwa birimo Phloretin.
Phloretin ifite ubushobozi bwo gucengera inzitizi yuruhu, imiti irwanya inflammatory, hamwe ningaruka zayo mukugabanya hyperpigmentation no kurinda ibyangiza ibidukikije, Phloretin ihagaze nkimbaraga zihindura mubuvuzi bwuruhu.
Nkumuhamagaro wibikorwa, turashishikariza abantu gushakisha ubushobozi bwibicuruzwa bivura uruhu birimo Phloretin, mugihe buri gihe dushyira imbere kurinda izuba no kugisha inama abahanga mugihe bashidikanya. Tangira uru rugendo rusanzwe rwo kwita ku ruhu, kandi wibonere ingaruka zihinduka za Phloretin wenyine. Reka ibidukikije na siyanse bihindure gahunda yawe yo kwita ku ruhu.
Igihe cyo kohereza: Ugushyingo-21-2023
