Ni izihe nyungu za Ginsenoside?

Intangiriro
Ginsenosideni urwego rwibintu bisanzwe biboneka mu mizi y’igihingwa cya Panax ginseng, kimaze ibinyejana byinshi gikoreshwa mu buvuzi gakondo bw’Abashinwa. Izi bioactive compound zimaze kwitabwaho cyane mumyaka yashize kubera inyungu zubuzima. Muri iki kiganiro, tuzasuzuma inyungu zinyuranye za ginsenoside, harimo n'ingaruka zabyo kumikorere yubwenge, guhindura sisitemu yumubiri, kurwanya anti-inflammatory, hamwe nibikorwa bishobora kurwanya antikanseri.

Imikorere yo kumenya

Imwe mu nyungu zizwi cyane za ginsenoside nubushobozi bwabo bwo kunoza imikorere yubwenge. Ubushakashatsi bwinshi bwerekanye ko ginsenoside ishobora kongera kwibuka, kwiga, hamwe nubumenyi rusange. Izi ngaruka zitekereza ko zahuzwa hakoreshejwe uburyo butandukanye, harimo no guhindura imitsi ya neurotransmitter, nka acetylcholine na dopamine, hamwe no guteza imbere neurogenezi, inzira yo kubyara neurone nshya mu bwonko.

Mu bushakashatsi bwasohotse mu kinyamakuru cya Ethnopharmacology, abashakashatsi basanze ginsenoside ishobora guteza imbere imyigire y’ahantu no kwibuka mu mbeba mu kongera imvugo y’imiterere ikomoka mu bwonko ikomoka mu bwonko (BDNF), poroteyine ifasha kubaho no gukura kwa neuroni. Byongeye kandi, ginsenoside yerekanwe kurinda indwara ziterwa no guta ubwenge hamwe n'indwara zifata ubwonko, nk'indwara ya Alzheimer na Parkinson, mu kugabanya imbaraga za okiside ndetse no gutwika mu bwonko.

Immune Sisitemu

Ginsenoside kandi yasanze ihindura imikorere y’umubiri, ikongerera ubushobozi bwo kwirinda indwara n'indwara. Izi miti zerekanwe gushimangira umusaruro nigikorwa cyingirabuzimafatizo zitandukanye, nka selile yica naturel, macrophage, na lymphocytes T, bigira uruhare runini mukurinda umubiri indwara ziterwa na kanseri na kanseri.

Ubushakashatsi bwasohotse mu kinyamakuru mpuzamahanga cyitwa Immunopharmacology bwerekanye ko ginsenoside ishobora kongera ubudahangarwa bw'umubiri ku mbeba byongera umusaruro wa cytokine, ibyo bikaba byerekana molekile igenga imikorere y'uturemangingo. Byongeye kandi, ginsenoside yerekanwe kuba ifite imiti irwanya virusi na anti-bagiteri, bigatuma iba umuti wizewe wo gushyigikira ubuzima bw’umubiri no kwirinda indwara.

Kurwanya Kurwanya

Gutwika ni igisubizo gisanzwe cya sisitemu yubudahangarwa ku gukomeretsa no kwandura, ariko gutwika karande bishobora kugira uruhare mu iterambere ry’indwara zitandukanye, zirimo indwara zifata umutima, diyabete, na kanseri. Ginsenoside yasanze ifite imbaraga zikomeye zo kurwanya inflammatory, zishobora gufasha kugabanya ingaruka mbi ziterwa n’umuriro udakira ku mubiri.

Ubushakashatsi bwasohotse mu kinyamakuru cy’ubushakashatsi bwa Ginseng bwerekanye ko ginsenoside ishobora guhagarika umusaruro wa cytokine itera umuriro kandi ikabuza gukora inzira zerekana ibimenyetso mu ngirabuzimafatizo. Byongeye kandi, ginsenoside yerekanwe kugabanya imvugo yabunzi batera umuriro, nka cyclooxygenase-2 (COX-2) hamwe na synthase ya nitric oxyde (iNOS), igira uruhare mugusubiza umuriro.

Igikorwa cya Anticancer

Ikindi gice gishishikajwe nubushakashatsi bwa ginsenoside nigikorwa cyabo gishobora kurwanya antikanseri. Ubushakashatsi bwinshi bwerekanye ko ginsenoside ishobora kugira ingaruka zo kurwanya kanseri mu guhagarika imikurire n’ikwirakwizwa ry’uturemangingo twa kanseri, gutera apoptose (gupfa ingirabuzimafatizo), no guhagarika ikibyimba angiogenezi (gushiraho imiyoboro mishya y'amaraso kugira ngo ikure ikure).

Ubushakashatsi bwasohotse mu kinyamakuru mpuzamahanga cy’ubumenyi bwa Molecular bwerekanye ubushobozi bwa anticancer ya ginsenoside, cyane cyane kanseri y'ibere, ibihaha, umwijima, na kanseri yibara. Isuzuma ryaganiriweho ku buryo butandukanye ginsenoside igira mu ngaruka zo kurwanya kanseri, harimo guhindura inzira zerekana ibimenyetso by'utugingo ngengabuzima, kugenzura iterambere ry'utugingo ngengabuzima, no kongera ubudahangarwa bw'umubiri urwanya kanseri.

Umwanzuro

Mu gusoza, ginsenoside ni bioactive compound iboneka muri Panax ginseng itanga inyungu nyinshi mubuzima. Ibi birimo kunoza imikorere yubwenge, guhindura imikorere yumubiri, kurwanya anti-inflammatory, hamwe nibikorwa bya anticancer. Mugihe hakenewe ubushakashatsi bwinshi kugirango dusobanukirwe neza nuburyo bwibikorwa nubushobozi bwo kuvura ginsenoside, ibimenyetso bihari byerekana ko ibyo bikoresho bitanga amasezerano nkumuti karemano wo guteza imbere ubuzima n’imibereho myiza muri rusange.

Reba
Kim, JH, & Yi, YS (2013). Ginsenoside Rg1 ihagarika imikorere ya selile dendritic no gukwirakwiza T selile muri vitro no muri vivo. Immunopharmacology mpuzamahanga, 17 (3), 355-362.
Leung, KW, & Wong, AS (2010). Pharmacology ya ginsenoside: gusubiramo ibitabo. Ubuvuzi bw'Abashinwa, 5 (1), 20.
Radad, K., Gille, G., Liu, L., Rausch, WD, & Gukoresha ginseng mu buvuzi hibandwa ku ndwara zifata ubwonko. Ikinyamakuru cya siyanse ya farumasi, 100 (3), 175-186.
Wang, Y., & Liu, J. (2010). Ginseng, ingamba zishobora kuba neuroprotective. Ubuvuzi bushingiye ku bimenyetso byuzuzanya n'ubundi buryo, 2012.
Yun, TK (2001). Intangiriro muri make ya Panax ginseng CA Meyer. Ikinyamakuru cyubumenyi bwubuvuzi bwa koreya, 16 (Suppl), S3.


Igihe cyo kohereza: Apr-16-2024
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