Ni izihe nyungu za Ginsenosides?

Imikorere yo mu bwenge

Imwe mu nyungu zizwi cyane za ginsenosides ni ubushobozi bwazo bwo kunoza imikorere y’ubwonko. Ubushakashatsi bwinshi bwagaragaje ko ginsenosides zishobora kongera kwibuka, kwiga, no gukora neza muri rusange kw’ubwonko. Izi ngaruka zifatwa nk’izituruka ku buryo butandukanye, harimo guhindura uburyo bwo gutuma imiyoboro y’ubwonko ikora, nka acetylcholine na dopamine, no guteza imbere uburyo bwo kororoka kw’ubwonko, inzira yo gukora imiyoboro mishya y’ubwonko.

Mu bushakashatsi bwasohotse mu kinyamakuru Journal of Ethnopharmacology, abashakashatsi basanze ginsenosides zishobora kunoza imyigire n’ubwitonzi mu mbeba binyuze mu kongera uburyo bwo kugaragaza neurotrophic factor (BDNF) ikomoka ku bwonko, poroteyine ifasha mu kubaho no gukura kw’uturemangingo tw’ubwonko. Byongeye kandi, ginsenosides byagaragaye ko zirinda indwara ziterwa no gusaza n’indwara zo mu bwonko, nka Alzheimer na Parkinson, binyuze mu kugabanya stress ya oxidative no kubyimba mu bwonko.

Ihindagurika ry'Ubudahangarwa bw'Indwara

Byagaragaye ko Ginsenosides ihindura ubudahangarwa bw'umubiri, yongera ubushobozi bwo kwirinda indwara n'ibindi. Ibi bintu byagaragaye ko bitera imbaraga mu gukora no gukora uturemangingo dutandukanye tw'ubudahangarwa bw'umubiri, nk'uturemangingo tw'umubiri twica karemano, macrophages, na T lymphocytes, bigira uruhare runini mu kwirinda indwara ziterwa n'udukoko n'uturemangingo twa kanseri.

Ubushakashatsi bwasohotse mu kinyamakuru International Immunopharmacology bwerekanye ko ginsenosides zishobora kongera ubushobozi bw'ubudahangarwa bw'umubiri mu mbeba binyuze mu kongera umusaruro wa cytokines, zigaragaza molekile zigenga imikorere y'uturemangingo tw'ubudahangarwa bw'umubiri. Byongeye kandi, byagaragaye ko ginsenosides zifite ubushobozi bwo kurwanya virusi na bagiteri, bigatuma ziba umuti karemano utanga icyizere mu gushyigikira ubuzima bw'ubudahangarwa bw'umubiri no gukumira indwara.

Imiterere irwanya ububyimbirwe

Kubyimba ni uburyo ubudahangarwa bw'umubiri butera imvune n'ubwandu, ariko kubyimba guhoraho bishobora kugira uruhare mu gutera indwara zitandukanye, harimo indwara z'umutima n'imitsi, diyabete na kanseri. Byagaragaye ko imiti ya Ginsenosides ifite ubushobozi bukomeye bwo kurwanya kubyimba, ishobora gufasha kugabanya ingaruka mbi z'ububyimba budakira ku mubiri.

Ubushakashatsi bwasohotse mu kinyamakuru Journal of Ginseng Research bwagaragaje ko ginsenosides zishobora kugabanya ikorwa rya cytokines zitera ubushyuhe no kubuza inzira z'ibimenyetso by'ubushyuhe mu turemangingo tw'umubiri gukora. Byongeye kandi, byagaragaye ko ginsenosides zigabanya uburyo ibintu bitera ubushyuhe bikorwa, nka cyclooxygenase-2 (COX-2) na inducible nitric oxide synthase (iNOS), bigira uruhare mu gusubiza ubushyuhe.

Igikorwa cyo kurwanya kanseri

Ikindi kintu gishimishije mu bushakashatsi bwa ginsenoside ni uko gishobora kurwanya kanseri. Ubushakashatsi bwinshi bwagaragaje ko ginsenosides zishobora kugira ingaruka ku ndwara ya kanseri mu kubuza ikura no kwiyongera kw'uturemangingo twa kanseri, bigatera apoptosis (urupfu rw’uturemangingo rwateguwe), no guhagarika angiogenesis ya tumor (iremwa ry’imitsi mishya y’amaraso kugira ngo ishyigikire ikura rya tumor).

Isuzuma ryasohotse mu kinyamakuru Mpuzamahanga cy’Ubumenyi bw’Ibinyabutabire ryagaragaje ubushobozi bwa ginsenosides bwo kurwanya kanseri, cyane cyane muri kanseri y’ibere, ibihaha, umwijima, n’indwara y’urura rurerure. Isuzuma ryagaragaje uburyo butandukanye ginsenosides zikoresha mu kurwanya kanseri, harimo guhindura inzira z’uturemangingo, kugenzura iterambere ry’uturemangingo, no kongera ubushobozi bw’ubudahangarwa bw’umubiri mu kurwanya uturemangingo twa kanseri.

Umwanzuro

Mu gusoza, ginsenosides ni ibintu bifatika biboneka muri Panax ginseng bitanga inyungu nyinshi ku buzima. Ibi birimo kunoza imikorere y'ubwonko, guhindura ubudahangarwa bw'umubiri, imiterere yo kurwanya ububyimbirwe, n'imikorere ishobora kurwanya kanseri. Nubwo hakenewe ubushakashatsi bwinshi kugira ngo dusobanukirwe neza uburyo ginsenosides zikora n'ubushobozi bwo kuvura, ibimenyetso bihari bigaragaza ko ibi bintu bifite icyizere nk'umuti karemano wo guteza imbere ubuzima bwiza muri rusange.

Amareferensi
Kim, JH, & Yi, YS (2013). Ginsenoside Rg1 igabanya gukora kw'uturemangingo twa dendritic no kwiyongera kw'uturemangingo twa T muri vitro no mu mubiri. International Immunopharmacology, 17 (3), 355-362.
Leung, KW, & Wong, AS (2010). Farumasi ya ginsenosides: isuzuma ry'inyandiko. Ubuvuzi bw'Abashinwa, 5(1), 20.
Radad, K., Gille, G., Liu, L., Rausch, WD, & Ikoreshwa rya ginseng mu buvuzi hibandwa ku ndwara zo kwangirika kw'imitsi. Ikinyamakuru cy'Ubumenyi bw'Imiti, 100(3), 175-186.
Wang, Y., & Liu, J. (2010). Ginseng, ingamba zishobora gukoreshwa mu kurinda ubwonko. Ubuvuzi bwuzuzanya n'ubundi buvuzi bushingiye ku bimenyetso, 2012.
Yun, TK (2001). Intangiriro muri make ya Panax ginseng CA Meyer. Ikinyamakuru cyubumenyi bwubuvuzi bwa koreya, 16 (Suppl), S3.