Nihe ijanisha rya Ginseng ni Ginsenoside?

Ginsenoside: Imvange ifatika muri Ginseng

Ginsenoside ni urwego rwibintu bisanzwe biboneka mu mizi y’igihingwa cya Panax ginseng, ndetse no mu yandi moko afitanye isano yo mu bwoko bwa Panax. Izi bioactive compound yihariye ginseng kandi ishinzwe ingaruka nyinshi za farumasi. Ginsenoside ni triterpene saponine, irangwa nuburyo butandukanye bwimiti nibikorwa byibinyabuzima.

Ijanisha rya ginsenoside muri ginseng rirashobora gutandukana bitewe nubwoko bwubwoko bwa ginseng, imyaka yikimera, imiterere ikura, nuburyo bwo kuyikuramo. Mubisanzwe, ibinini bya ginsenoside byose bikoreshwa nkigipimo cyubwiza nubushobozi bwibicuruzwa bya ginseng, kuko byerekana ubunini bwibintu bikora bishinzwe ingaruka zo kuvura.

Ijanisha rya Ginsenoside muri Ginseng

Ijanisha rya ginsenoside muri ginseng irashobora kuva kuri 2% kugeza kuri 6% mumuzi, hamwe nubwoko butandukanye bitewe nubwoko bwihariye nigice cyigihingwa cyakoreshejwe. Kurugero, ginseng itukura yo muri koreya, itegurwa no guhumeka no gukama imizi ya ginseng, mubisanzwe irimo ijanisha ryinshi rya ginsenoside ugereranije na ginseng mbisi. Byongeye kandi, kwibumbira hamwe kwa ginsenoside kugiti cya ginsenoside byose birashobora gutandukana, hamwe na ginsenoside iba myinshi cyane kuruta iyindi.

Ijanisha rya ginsenoside rikoreshwa kenshi nk'ikimenyetso cyerekana ubuziranenge n'imbaraga z'ibicuruzwa bya ginseng. Ijanisha ryinshi rya ginsenoside muri rusange rifitanye isano nubushobozi bukomeye bwo kuvura, kubera ko ibyo bikoresho bivugwa ko ari byo nyirabayazana w’ingaruka za farumasi ya ginseng, harimo na adaptogenic, anti-inflammatory, na immun-modulation.

Akamaro k'ibirimo bya Ginsenoside

Ijanisha rya ginsenoside muri ginseng ni ingenzi kubwimpamvu nyinshi. Ubwa mbere, ikora nkigipimo cyubwiza nukuri kwibicuruzwa bya ginseng. Ijanisha ryinshi rya ginsenoside yerekana ubwinshi bwibintu bikora, bikaba byifuzwa kugera kubintu byifuzwa byo kuvura. Kubwibyo, abaguzi nababikora bakunze gushakisha ibicuruzwa bya ginseng bifite ibintu byinshi bya ginsenoside kugirango barebe neza.

Icya kabiri, ijanisha rya ginsenoside irashobora kugira ingaruka kuri bioavailable na pharmacokinetics yibicuruzwa bya ginseng. Kwiyongera kwinshi kwa ginsenoside birashobora gutuma umuntu yinjira cyane kandi akwirakwiza ibyo bintu mu mubiri, bishobora kongera ingaruka zo kuvura. Ibi ni ingenzi cyane kubwinyongera ya ginseng no gutegura ibyatsi, aho bioavailable ya ginsenoside ishobora kugira ingaruka kumikorere yabo.

Ingaruka zo Kugenzura Ubuziranenge no Kuringaniza

Ijanisha rya ginsenoside muri ginseng rifite ingaruka zo kugenzura ubuziranenge no kugena ibicuruzwa bya ginseng. Kugereranya ibimera bya ginseng bishingiye kubirimo bya ginsenoside bituma habaho guhuzagurika mubigize imbaraga nimbaraga zateguwe na ginseng, byemeza ko abaguzi bahabwa ibicuruzwa byizewe kandi byiza.

Ingamba zo kugenzura ubuziranenge, nka chromatografiya ikora cyane (HPLC) hamwe na sprometrike rusange, ikoreshwa muburyo bwo kugereranya ibirimo ginsenoside mubicuruzwa bya ginseng. Ubu buhanga bwo gusesengura butuma hamenyekana neza ijanisha rya ginsenoside, kimwe no kumenya no kugereranya ginsenoside ku giti cye iboneka mu gice.

Byongeye kandi, inzego zishinzwe kugenzura n’imiryango y’inganda zishobora gushyiraho umurongo ngenderwaho n’ibisobanuro bya ginsenoside yibicuruzwa bya ginseng kugirango ubuziranenge n'umutekano. Ibipimo ngenderwaho bifasha kurinda abakiriya ibicuruzwa byangiritse cyangwa bitujuje ubuziranenge no guteza imbere gukorera mu mucyo no gukorera mu mucyo mu nganda za ginseng.

Umwanzuro
Mu gusoza, ijanisha rya ginsenoside muri ginseng ningingo nyamukuru igena ubuziranenge bwayo, imbaraga, hamwe nubuvuzi bwiza. Ijanisha ryinshi rya ginsenoside muri rusange rifitanye isano ningaruka zikomeye za farumasi, bigatuma bifuza abaguzi bashaka inyungu zubuzima bwa ginseng. Kugena ibicuruzwa bya ginseng bishingiye kubirimo bya ginsenoside no gushyira mubikorwa ingamba zo kugenzura ubuziranenge nibyingenzi kugirango habeho guhuza no kwizerwa kwimyiteguro ya ginseng. Mugihe ubushakashatsi bukomeje kwerekana ubushobozi bwo kuvura ginsenoside, ijanisha ryibi binyabuzima muri ginseng bizakomeza kuba ikintu cyingenzi mugusuzuma no gukoresha uyu muti wibyatsi.

Reba
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Kim, JH (2012). Ubuvuzi bwa farumasi nubuvuzi bwa Panax ginseng na ginsenoside: isubiramo ryo gukoresha mu ndwara zifata umutima. Ikinyamakuru cya Ginseng Ubushakashatsi, 36 (1), 16-26.
Vuksan, V., Sievenpiper, JL, & Koo, VY (2008). Ginseng y'Abanyamerika (Panax quinquefolius L) igabanya glycemia nyuma yo kwanduzwa mu ngingo zitari diyabete hamwe n’indwara ya diyabete yo mu bwoko bwa 2. Ububiko bw'Ubuvuzi bw'imbere, 168 (19), 2044-2046.