I. IRIBURIRO
Intangiriro
Ginkgo Ikibabini ikintu gikora gisanzwe cyakuwe mu mababi ya Ginkgo. Ibice byayo nyamukuru ni flavonoides na Ginkgo amabuye. Nibintu byihariye bya paf (ibintu bya plaquet-gukora, ibintu bya plaque-gukora-gukora) kwakira antagonist. Ibikorwa bya farumasi birimo: Kunoza imyigaragambyo no kuzenguruka no muri Metabolism; Kongera ibikorwa byamaraso yumutuku wa superoxide ya superoxide (sod) na gsh-px), no kugabanya selile membranes pepideri pepidides (MDA). Umusaruro, gusubizwa imirasire yubusa, irinde ibyangiritse kuri Cardiomytes hamwe na Votimale ya Endoteliyali; guhitamo kurwanya platelet comgrelet, micro trombose, na lipid metabolism za lipdarism zatewe na plaque paf; Gutezimbere urutonde rwumutima kandi urinde Ischemimium Myocardium; Ongera ubumuga bwa selile zitukura, kugabanya uruyobe rwamaraso, kandi ukureho imvururu za microcindare; kubuza synthesis ya throxane (txa2) no gukangura irekurwa rya prostaglandin pgi2 uhereye kuri selile zamaso ya vascular.
Inkomoko y'ibimera
Ginkgo Biloba ni ikibabi cya Ginkgo Biloba L., igihingwa cyumuryango wa Ginkgo. Gukuramo kwayo (EgB) bifite imirimo itandukanye yubuzima kandi ikoreshwa cyane mubiryo no kwisiga. Ibigize imiti byibabi rya ginkgo biragoye cyane, hamwe nibice birenga 140 byitaruye. Flavonoide na teperperatoons nibice bibiri byingenzi bigize ginkgo. Byongeye kandi, irimo kandi gupimapi, aside kama, polysakecchaside, aside amino, ibibazo, hamwe nibisobanuro. Dukurikije imibare ituzuye, ubu buryo mpuzamahanga buriho gisanzwe ginkgo ni egb761 yakozwe hakurikijwe inzira ya Schwabe y'Ubudage. Bigaragara nkifu yumuhondo-yumuhondo kandi ifite impumuro nkeya ya ginkgo ikibabi. Ibigize imiti ni 24% Flavonoide, 6% Amarenge Amabuye, munsi ya 0,0005% Ginkgo Acid, imyaka 7.0%, 20% %, ubuhanga budasanzwe 5.0%, ubuhehere bwo gukemura 3.0%, abandi 3.0%.
Ingingo ya AntioExide
Ginkgo Ibibabi bya Ginkgo birashobora gukuraho mu buryo butaziguye imirasire yubusa, lipid peroxidation yubusa alkane kubuntu, nibindi, hanyuma uhagarike urunigi rwubusa. Muri icyo gihe, irashobora kandi kugena no kunoza ibikorwa bya antioxidant enzymes nka superoxide demeroxide na glutathione peroxidase. Ingaruka ya Antioxident ya Flavonoide muri Egb irenze vitamine, kandi ifite imitungo idasanzwe yubusa muri vitro.
Ingaruka za Antioxydidant zikomoka kuri Ginkgo zashyizwe muburyo butandukanye ziratandukanye, kandi ingaruka za Antioxident zikuramo kandi ibicuruzwa binonosoye nabyo bitandukanye. MA Xihan Et al. Habonetse ko petroleum Ether-Ethanol yagira ingaruka zikomeye kuri Antioxident kumavuta yingufu ugereranije nibisohokamo bya ginkgo byabonetse muburyo butandukanye bwo gutegura. Ubushobozi bwa Antioxident yo gukuramo ibibabi bya ginkgo byari hejuru gato kurenza ibyuma. Ibi birashobora guterwa nubugome burimo ibindi bikoresho bya Antioxident, nka Acide Ofrican, acide amino, tannine, alkaloide afite ingaruka zidafite ibitekerezo.
Uburyo bwo gutegura
. Kubera ko ayandi makosa ari uburozi cyangwa ihindagurika, ethanol muri rusange ikoreshwa nkumukozi ukuramo. Ubushakashatsi bwanditswe na Zhang Yonghong nabandi byerekanaga ko ibihe byiza byo gukuramo flavonoide ibibabi bya ginkgo ni 9:20, kandi buri gihe, kubeshya amasaha 1.5.
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. Kubwibyo, ultrasonic yo gukuramo flavonoide ifite ibyiza byinshi. Ibisubizo byubushakashatsi byabonetse na Liu Jingzhi et al. Erekana ko inzira yo gukuramo ultrasonic ikuramo: Ultrasonic Frequency 40khz, Ultrasonic Igihe cyo kuvura 55min, ubushyuhe 35 ° C, no guhagarara kuri 3h. Muri iki gihe, igipimo cyo gukuramo ni 81.9%.
Gusaba
Flavonoide mumababi ya Ginkgo afite imiterere ya antioxident kandi irashobora kongerwaho amavuta na rohosike nka antioxidants. Flavonoids yose ni umuhondo kandi ifite ibibazo byinshi, byombi bishonga amazi hamwe nibinure, bityo flavonoide yose irashobora gukoreshwa mugusiga amabara. ingaruka. Ginkgo biloba itunganijwe muri ifu ya ultrafine hanyuma yongera kubiryo. Ibibabi bya Ginkgo ni ultra-byiza cyane kandi byongewe kuri cake, biscuits, amazu, bombo, na ice cream ku gipimo cya 5% kugeza ku bibabi bya ginkgo hamwe ningaruka zubuzima.
Ibibabi bya Ginkgo bikoreshwa nk'ibiryo byongewe muri Kanada kandi byemejwe nk'ibiyobyabwenge birenze ubudage n'Ubufaransa. Ikibabi cya Ginkgo cyashyizwe muri Pharmacopoeia zunze ubumwe za Amerika (Edition 24) kandi zirashobora gukoreshwa nk'inyongera yimirire muri Amerika.
Ingaruka za Farmacologi
1. Ingaruka kuri sisitemu yumutima
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. Irashobora kubuza imbaraga za Cordiac zatewe na allergie ya Cardiac mumashusho ya Gineya.
. Gukuramo ibibabi bya Ginkgo birashobora kubuza ubwiyongere bwa microvascular microvascular diameter yatewe na intravenous endotoxin. Muri Canine Endotoxin, Ginkgo Biloba gukuramo ibibuza impinduka ziwe; Muri Modeli y'ibiro by'intama, Ginkgo Biloba gukuramo ibibuza hypersension na edema ya ludema iterwa n'indwara ya lymphatic iterwa na endotoxin.
. Nyuma yiminsi 40, Sermu Triglyceride yagabanutse cyane. Ginkgo Biloba gukuramo (20 mg / kg kumunsi) yatanzwe kumunwa kurubuga rusanzwe kandi hypercholesterolemic. Nyuma yukwezi kumwe, urwego rwa cholesteroli ya hyper-sholesterol muri plasma na aorta yinkwavu bakira indyo ya Atherogenic yagabanutse cyane. Icyakora urwego rwa cholesterol kubuntu ntiguhindutse.
(5) Ginkgo terpene lactone ni paffe yihariye ya paf yakira. Ginkgo Ikibabi cyangwa Ginkgo Terpene Carpene irashobora kubuza ibintu bitangaje (Paf) na CyclooxyGesease cyangwa LipoxyGenase. Ginkgo Ibibabi bya Ginkgo byari byihanganirwa neza kandi bigabanya ubukana bwa platelet cyatewe na paf ariko ntibyagize ingaruka ku kwiyongera kwatewe na ADP.
2. Ingaruka kuri sisitemu yo hagati
. Irashobora guteza imbere ubwonko buzenguruka ubwonko no kunoza imikorere yo kwibuka.
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. Kuzamura imikorere yimbwa nyuma yuburyo bwo mu bwonko Ischemia hakiri kare cyane Neuronal no Kugabanya ibyangiritse bya Neuronia nyuma y'isi nini ya Gerbil; Kugabanya cyane gutakaza ATP, AMP, Cremtine na Creat Forephate mu bwonko bwisi bwimbwa ya Mongrel. Ginkgo Biloba Lacto LocTone B ni ingirakamaro muburyo bwo kuvura indwara ya stroke.
3. Ingaruka kuri sisitemu yo gusya
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. Ibi byerekana ko ibibabi bya ginkgo bituma habaho ingaruka zo kuvura kumurongo cirrhose. Irashobora guhagarika imiterere ya ogisijeni-yubusa mu mbeba ikaze pancreatite yatewe na kolecystokinin. Ginkgo Terpene Lacgo Inpene B irashobora kugira uruhare mukuvura pancreatite ikaze.
4. Ingaruka kuri sisitemu yubuhumekero
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. Ibibabi bya Ginkgo Ibisohoka bifite akamaro gakomeye mu kubuza no kuvura hreepesined.
5. Ingaruka yo kurwanya anti-an
Ginkgobiflavnoides, Indoginkgobiflavnonides, Ginkgo Biloba, na Qingotin muri Ginkgo yasize bose ibuza lipid proxidation, cyane cyane ko Quercetin ifite ibikorwa bikomeye bibuza. Ubushakashatsi bwakorewe ku mbeba kandi byagaragaye ko ibibabi bya ginkgo yakuweho amazi meza (0.95mg / ML
7. Uruhare muguhinduranya kwangwa hamwe nibindi bihunyike
Ginkgo Ikibabi Irashobora kuramba igihe cyo kubaho cyuruhu rwuruhu rwuruhu, umutima wa heterotopic xenopics, na orhotopic umwijima wa xenopic. Gukuramo ibibabi bya Ginkgo birashobora kubuza ibikorwa byumubiri byumubiri byica selile za KC526, kandi birashobora kandi gukumira ibikorwa bya killer bisanzwe byatewe na interferon.
8. Ingaruka yo kurwanya ibibyimba
Igishushanyo mbonera cy'icyatsi kibisi cya Ginkgo Biloba, igice cyoroshye, gishobora kubuza virusi ya EPSTEI-Barr. Heptadecene SALICYLULCLULCULCULCLUCHLULCULCULCLUCH flavonoide zose za ginkgo irashobora kongera uburemere bwaho bwimbeba zitwara ibibyimba. na sod ibikorwa byibikorwa, gukangurira umubiri urwanya ubushobozi bwo kurwanya ibibyimba; Quercetin na MyCitine birashobora kubuza kubaho kwa karugero.
Inyandiko hamwe nibyambukiranya
Ibisubizo bibi byo gukuramo ibibabi bya Ginkgo: Rimwe na rimwe muri anorexia, isesemiya, insinga, intebe zirekuye, insinga zo munda, nibindi .; Hashobora kandi kwiyongera kumutima, umunaniro, nibindi, ariko ibi ntibigira ingaruka kumiti. Nyuma yubuyobozi bwigihe kirekire, ibipimo bifatika byerekana imiterere yamaraso bigomba gusubirwamo buri gihe. Niba ufite ibimenyetso byinshi, urashobora kuyijyana nyuma yo kurya aho.
Imikoranire y'ibiyobyabwenge
Iki gicuruzwa gifite ingaruka zikoreshwa mugihe zikoreshwa hamwe nizindi miti igabanya amaraso, nka sodium alungite asteri, acetate, nibindi, bishobora guteza imbere imikorere.
Iterambere
Ibibabi bya Ginkgo birimo umubare muto wa proanthocyanidins na aside arishiolic, ibigifite uburozi kumubiri wumuntu. Iyo amababi ya ginkgo ameze ibikoresho fatizo byo gutunganya ibiryo, ubuvuzi bwihariye burasabwa kugabanya ibikubiye muri Proanthocyanidins na ACIDS. Ariko, muri iki gihe cyakoreshejwe kumurongo, nta burozi bukabije cyangwa budakira kandi nta ngaruka za teratogenic. Minisiteri y'ubuzima yemeye guloba gukuramo nk'ibiribwa bishya mu 1992. Mu myaka yashize, Ginkgo Bilooide yakoreshejwe cyane mu nganda z'ibiribwa, n'ubushakashatsi n'iterambere rya Ginkgo Biloba ifite ibyiringiro byinshi.
Twandikire
Ubuntu Hu (Umuyobozi wamamaza)grace@biowaycn.com
Carl Cheng (Umuyobozi mukuru / Boss)ceo@biowaycn.com
Urubuga:www.biowaynutrition.com
Igihe cyohereza: Sep-12-2024
