Gutanga Uruganda rutanduye β-Nicotinamide adenine dinucleotide (NAD)
β-Nicotinamide adenine dinucleotide (NAD) ni coenzyme iboneka mu ngirabuzimafatizo zose, igira uruhare runini mu nzira zitandukanye. Ni ngombwa kubyara ingufu, gusana ADN, no kwerekana ibimenyetso. NAD ibaho muburyo bubiri: NAD + na NADH, bigira uruhare mubitekerezo bya redox, guhererekanya electron mugihe cyinzira ya metabolike. NAD ni ingenzi mu kubungabunga imikorere ya selile nubuzima muri rusange, kandi urwego rwayo rushobora kugira ingaruka kumikorere itandukanye. Ikoreshwa cyane mu buhanga mu bya farumasi, ibinyabuzima, n’inganda zikora ibiribwa, ndetse no mu gukora inyongeramusaruro n’ibiribwa bikora bigamije ingufu za metabolisme n’ubuzima bw’akagari. Mugihe cyuruganda, NAD irashobora kubyara binyuze muri fermentation, ikoresheje mikorobe kugirango ihindure molekile ibanziriza NAD. Igikorwa cyo kubyaza umusaruro gikubiyemo kugenzura neza imiterere ya fermentation kugirango uhindure ihinduka ryabanjirije muri NAD.
| Ingingo | Agaciro |
| URUBANZA No. | 53-84-9 |
| Andi mazina | beta-Nicotinamide adenine dinucleotide |
| MF | C21H27N7O14P2 |
| EINECS No. | 200-184-4 |
| Aho byaturutse | Ubushinwa |
| Andika | Abahinzi ba Agrochemiki, Abahuza Dyestuff, Flavour & Fragrance Intermediates, Syntheses Material Intermediates |
| Isuku | 99% |
| Gusaba | Syntheses Material Intermediates |
| Kugaragara | Ifu yera |
| Izina | beta-Nicotinamide adenine dinucleotide |
| MW | 663.43 |
| MF | C21H27N7O14P2 |
| Ifishi | Birakomeye |
| Kugaragara | Ifu yera |
| MOQ | 1kg |
| Ingero | Birashoboka |
| Ubuzima bwa Shelf | Imyaka 2 |
Isuku ryinshi:NAD yacu ikorwa hifashishijwe uburyo bugezweho bwo gukora kugirango tumenye neza, byujuje ubuziranenge bukomeye busabwa mu bya farumasi, ibinyabuzima, hamwe n’ibiribwa.
Ubwiza buhoraho:Turakomeza ingamba zifatika zo kugenzura ubuziranenge mubikorwa byose kugirango tubyare umusaruro kugirango ibicuruzwa byacu bya NAD bihore byujuje ibisabwa n'ibipimo ngenderwaho.
Porogaramu zitandukanye:NAD yacu irashobora gukoreshwa muburyo butandukanye bwo gukoresha, harimo imiti, inyongeramusaruro, ibiryo bikora, hamwe na biotechnologie, kubera uruhare runini muri metabolism selile no kubyara ingufu.
Kubahiriza amabwiriza:Ibicuruzwa byacu bya NAD byubahiriza ibipimo ngenderwaho mpuzamahanga, byemeza kubahiriza amabwiriza n'amabwiriza bijyanye n'umutekano n'ubuziranenge.
Isoko ryizewe:Dufite ubushobozi bwo kubyaza umusaruro hamwe nubushobozi bwo gutanga ibikoresho kugirango dutange isoko yizewe kandi ihamye ya NAD kugirango duhuze ibyifuzo byabakiriya bacu.
Inkunga ya tekiniki:Itsinda ryinzobere zacu zirashobora gutanga ubufasha bwa tekiniki nubuyobozi mugukoresha NAD mubikorwa bitandukanye, byemeza ko abakiriya bacu bashobora kugwiza inyungu kubicuruzwa byacu.
Muri rusange, ibicuruzwa byacu bya NAD birangwa nubuziranenge bwabyo, ubuziranenge buhoraho, guhuza byinshi, kubahiriza amabwiriza, gutanga amasoko yizewe, hamwe nubufasha bwa tekiniki bwuzuye, bigatuma biba byiza mubikorwa bitandukanye byinganda nubucuruzi.
Pure β-Nicotinamide adenine dinucleotide (NAD) itanga imirimo myinshi nibyiza byubuzima, harimo:
Umusaruro w'ingufu:
NAD igira uruhare runini mukubyara adenosine triphosphate (ATP), ifaranga ryibanze ryingirabuzimafatizo. Mu kwitabira reaction ya redox, NAD yorohereza ihererekanyabubasha rya electron mugikorwa cya fosifori ya okiside, ningirakamaro mu kubyara ATP muri mitochondria.
Metabolism ya selile:
NAD igira uruhare munzira zitandukanye zo guhinduranya, harimo glycolysis, aside tricarboxylic (TCA), hamwe na okiside ya aside irike. Izi nzira ningirakamaro mugusenyuka no gukoresha intungamubiri zibyara ingufu nibikorwa bya selile.
Gusana ADN:
NAD ni co-substrate ya enzymes igira uruhare mubikorwa byo gusana ADN, nka polymerase ya poly (ADP-ribose) (PARPs) na sirtuins. Iyi misemburo igira uruhare runini mukubungabunga ituze rya genomic no gusana ibyangiritse kuri ADN biterwa nimpungenge zitandukanye.
Ibimenyetso by'akagari:
NAD ikora nka substrate ya sirtuins, icyiciro cya poroteyine zigira uruhare mugutunganya imikorere ya selile nko kwerekana gene, apoptose, hamwe no gukemura ibibazo. Sirtuins igira uruhare mu kuramba kandi byahujwe n’inyungu zishobora kubaho ku buzima.
Inyungu zishobora kubaho mu buzima:
Ubushakashatsi bwerekana ko kuzuza NAD cyangwa guhindura urwego rwa NAD bishobora kugira ubuzima bwiza, harimo no gushyigikira imikorere ya mito-iyambere, guteza imbere gusaza neza, ndetse n’ingaruka zishobora guterwa n’imikorere mibi ya metabolike no guhangayika.
Pure β-Nicotinamide adenine dinucleotide (NAD) ifite porogaramu zitandukanye mu nganda zinyuranye kubera uruhare runini muri metabolism selile no kubyara ingufu. Bimwe mubikorwa byingenzi bya NAD byuzuye birimo:
Inganda zimiti:
NAD ikoreshwa nkigice cyingenzi mubikorwa bya farumasi, cyane cyane mumiti yibasira indwara ziterwa na metabolike, imikorere mibi ya mitochondial, hamwe nibihe bijyanye n'imyaka. Irakoreshwa kandi mubushakashatsi niterambere mugushobora kuvura.
Ibiryo byongera ibiryo:
NAD yinjizwa mubyokurya bigamije gushyigikira ubuzima bwimikorere ya selile, metabolisme yingufu, nubuzima bwiza muri rusange. Izi nyongera zicuruzwa kubushobozi bwabo bwo guteza imbere gusaza neza no gukora metabolike.
Ibiribwa n'ibinyobwa bikora:
NAD ikoreshwa mugutezimbere ibiryo n'ibinyobwa bikora bigamije gushyigikira umusaruro w'ingufu, ubuzima bwa selile, hamwe no kuringaniza metabolike. Ibicuruzwa birashobora kwibasira abakiriya bashaka inzira karemano zo kuzamura ubuzima bwabo muri rusange.
Ikoranabuhanga mu binyabuzima:
NAD ikoreshwa muburyo butandukanye bwibinyabuzima, harimo umuco w'utugari, fermentation, hamwe na enzyme yubuhanga. Ikora nka cofactor ikomeye muburyo bwinshi bwimikorere ya enzymatique hamwe ninzira ya metabolike, ikagira agaciro mubikorwa bya bioprocessing na biomanufacturing.
Ubushakashatsi n'Iterambere:
NAD ikoreshwa nkigikoresho cyubushakashatsi muri laboratoire y’inganda n’inganda mu kwiga metabolism selile, umusaruro w’ingufu, hamwe n’inyungu zishobora kubaho ku buzima zijyanye no guhindura NAD. Ni ingingo kandi yubushakashatsi bwa siyanse ku ngaruka zayo mu gusaza, indwara ziterwa na metabolike, hamwe n’imiterere ya neurodegenerative.
Cosmeceuticals:
NAD yinjizwa mubuvuzi bwuruhu no kwisiga kugirango bushobore gushyigikira ubuzima bwimikorere nubuzima. Igurishwa nkibigize ibintu birwanya gusaza no kuvugurura ibintu.
Ibicuruzwa byacu bishingiye ku bimera byakozwe hifashishijwe ingamba zikomeye zo kugenzura ubuziranenge kandi byubahiriza ibipimo bihanitse byo gutunganya umusaruro. Dushyira imbere umutekano nubuziranenge bwibicuruzwa byacu, tukemeza ko byujuje ibisabwa n’amabwiriza y’inganda. Uku kwiyemeza ubuziranenge bigamije gushiraho ikizere nicyizere mubicuruzwa byacu. Ibikorwa rusange byumusaruro nuburyo bukurikira:
Ububiko: Bika ahantu hakonje, humye, kandi hasukuye, Kurinda ubushuhe n’umucyo utaziguye.
Igipapuro kinini: 25kg / ingoma.
Igihe cyo kuyobora: iminsi 7 nyuma yo gutumiza.
Ubuzima bwa Shelf: imyaka 2.
Icyitonderwa: Ibisobanuro byihariye nabyo birashobora kugerwaho.
25kg / urubanza
Gupakira neza
Umutekano wibikoresho
Express
Munsi ya 100kg, Iminsi 3-5
Serivisi ku muryango byoroshye gufata ibicuruzwa
Ku nyanja
Kurenga 300 kg, Hafi Iminsi 30
Icyambu kugeza ku cyambu serivisi yumwuga yemewe arakenewe
Na Air
100kg-1000kg, Iminsi 5-7
Ikibuga cyindege cya serivise yikibuga cyumwuga gikenewe
Bioway yunguka ibyemezo nka USDA na EU ibyemezo bya organic, ibyemezo bya BRC, ibyemezo bya ISO, ibyemezo bya HALAL, na KOSHER.
