Isoko ry'uruganda ryitwa β-Nicotinamide adenine dinucleotide (NAD) ryuzuye
β-Nicotinamide adenine dinucleotide (NAD) ni coenzyme iboneka mu turemangingo twose tuzima, igira uruhare runini mu mikorere itandukanye ya metabolism. Ni ingenzi mu gukora ingufu, gusana ADN, no gutanga ibimenyetso ku turemangingo. NAD ibaho mu buryo bubiri: NAD+ na NADH, bigira uruhare mu mikorere ya redox, bigatwara electron mu nzira za metabolism. NAD ni ingenzi mu kubungabunga imikorere y'uturemangingo n'ubuzima rusange, kandi urwego rwayo rushobora kugira ingaruka ku mikorere itandukanye ya physiological. Ikoreshwa cyane mu miti, biotechnology, n'inganda z'ibiribwa, ndetse no mu gukora inyongeramusaruro n'ibiribwa bikora neza bigamije metabolism y'ingufu n'ubuzima bw'uturemangingo. Mu ruganda, NAD ishobora gukorwa binyuze mu gushyushya, ikoresheje mikorobe kugira ngo ihindure molekile za precursor muri NAD. Uburyo bwo kuyikora busaba kugenzura neza imiterere ya fermentation kugira ngo ibintu bya precursor bihindurwe NAD.
| Ikintu | Agaciro |
| Nimero ya CAS | 53-84-9 |
| Andi Mazina | beta-Nicotinamide adenine dinucleotide |
| MF | C21H27N7O14P2 |
| EINECS No. | 200-184-4 |
| Aho yaturutse | Ubushinwa |
| Ubwoko | Ibikoresho byo mu buhinzi, Ibikoresho byo mu bwoko bwa Dyestuff, Ibikoresho byo mu bwoko bwa Avour & impumuro nziza, Ibikoresho byo mu bwoko bwa Syntheses |
| Ubwiza | 99% |
| Porogaramu | Ibikoresho byo mu rwego rwo hagati |
| Isura | Ifu y'umweru |
| Izina | beta-Nicotinamide adenine dinucleotide |
| MW | 663.43 |
| MF | C21H27N7O14P2 |
| Ifishi | Bikomeye |
| Isura | Ifu y'umweru |
| MOQ | 1kg |
| Ingero | Biraboneka |
| Igihe cyo Kubika | Imyaka 2 |
Ubwiza Buhanitse:NAD yacu ikorwa hakoreshejwe uburyo bugezweho bwo gukora kugira ngo igire isuku yo hejuru, yujuje ibisabwa mu bijyanye n'imiti, ikoranabuhanga rya bio, n'ibiribwa.
Ubwiza buhoraho:Dukomeza ingamba zikomeye zo kugenzura ubuziranenge mu gihe cyose cyo gukora kugira ngo turebe ko ibicuruzwa byacu bya NAD byujuje ibisabwa n'ibipimo ngenderwaho by'imikorere.
Porogaramu zikoreshwa mu buryo butandukanye:NAD yacu ishobora gukoreshwa mu bintu bitandukanye, harimo imiti, inyongeramusaruro, ibiryo bikora neza, n'imikorere y'ikoranabuhanga rya biotechnological, bitewe n'uruhare rwayo mu mikorere y'uturemangingo no mu gukora ingufu.
Iyubahirizwa ry'amategeko agenga iyubahirizwa ry'amategeko:Ibicuruzwa byacu bya NAD byubahirije amahame mpuzamahanga agenga imikorere, bikubahiriza amabwiriza n'amabwiriza ajyanye n'umutekano n'ubuziranenge.
Itangwa ryizewe:Dufite ubushobozi bwo gukora no gutunganya ibikoresho kugira ngo dutange serivisi zizewe kandi zihoraho za NAD kugira ngo duhuze ibyifuzo by'abakiriya bacu.
Inkunga ya tekiniki:Itsinda ryacu ry'inzobere rishobora gutanga ubufasha mu bya tekiniki n'ubuyobozi ku ikoreshwa rya NAD mu bikorwa bitandukanye, rigamije kwemeza ko abakiriya bacu bashobora kubyaza umusaruro ibicuruzwa byacu.
Muri rusange, ibicuruzwa byacu bya NAD birangwa no kuba bifite isuku yo hejuru, ubwiza buhoraho, ubushobozi bwo gukora ibintu bitandukanye, kubahiriza amategeko, gutanga ibicuruzwa byizewe, hamwe n'ubufasha bwa tekiniki bwuzuye, bigatuma biba byiza cyane mu bikorwa bitandukanye by'inganda n'ubucuruzi.
Pure β-Nicotinamide adenine dinucleotide (NAD) itanga imirimo myinshi n'inyungu zishobora kubaho ku buzima, harimo:
Umusaruro w'ingufu:
NAD igira uruhare runini mu gukora adenosine triphosphate (ATP), ifaranga ry’ingufu z’ibanze mu ngirabuzimafatizo. Mu kwitabira redox reactions, NAD yoroshya ihererekanya rya electron mu gikorwa cya oxidative phosphorylation, ikaba ari ingenzi mu gukora ATP muri mitochondria.
Ihinduka ry'uturemangingo:
NAD igira uruhare mu nzira zitandukanye za metabolisme, harimo glycolysis, cycle ya aside tricarboxylic (TCA), na oxidation ya aside fatty. Izi nzira ni ingenzi mu gusenya no gukoresha intungamubiri mu gukora ingufu no gukora neza kw'uturemangingo.
Gusana ADN:
NAD ni igice kimwe cy’imisemburo ikora mu gusana ADN, nka poly(ADP-ribose) polymerases (PARPs) na sirtuines. Izi enzymes zigira uruhare runini mu kubungabunga ihindagurika rya genome no gusana ibyangiritse bya ADN biterwa n’ibintu bitandukanye bitera stress.
Ibimenyetso bya Seli:
NAD ikora nk'ishingiro rya sirtuines, ubwoko bwa poroteyine zigira uruhare mu kugenzura imikorere y'uturemangingo nko kugaragaza imiterere y'uturemangingo, apoptosis, no gusubiza stress. Sirtuines zifite uruhare mu kuramba kandi zagiye zifitanye isano n'inyungu zishobora kubaho ku buzima.
Ibyiza Bishoboka ku Buzima:
Ubushakashatsi bwerekana ko kongera cyangwa guhindura urugero rwa NAD muri NAD bishobora kugira akamaro ku buzima, harimo gushyigikira imikorere ya mitochondrial, guteza imbere gusaza neza, ndetse no kugira ingaruka ku buzima bujyanye no kudakora neza kwa metabolic ndetse no guhangayika mu turemangingo.
Pure β-Nicotinamide adenine dinucleotide (NAD) ifite akamaro kanini mu nganda zitandukanye bitewe n'uruhare rwayo mu mikorere y'uturemangingo no mu gukora ingufu. Zimwe mu nshingano z'ingenzi za pure NAD zirimo:
Inganda zikora imiti:
NAD ikoreshwa nk'igice cy'ingenzi mu mikorere y'imiti, cyane cyane mu miti yibasira indwara za metabolisme, imikorere mibi ya mitochondrial, n'indwara ziterwa n'izabukuru. Ikoreshwa kandi mu bushakashatsi no mu iterambere ry'uburyo bwo kuvura bushobora kubaho.
Inyongeramusaruro ku mirire:
NAD ishyirwa mu nyongeramusaruro zigamije gushyigikira ubuzima bw'uturemangingo, imikorere y'ingufu, n'imibereho myiza muri rusange. Izi nyongeramusaruro zicuruzwa kubera ubushobozi bwazo bwo guteza imbere gusaza no gukora neza kw'ingufu.
Ibyokurya n'ibinyobwa bifite akamaro:
NAD ikoreshwa mu guteza imbere ibiryo n'ibinyobwa bikora neza bigamije gushyigikira ikorwa ry'ingufu, ubuzima bw'uturemangingo, no kuringaniza imikorere y'umubiri. Ibi bicuruzwa bishobora kwibasira abaguzi bashaka uburyo busanzwe bwo kongera ubuzima bwabo muri rusange n'imbaraga zabo.
Ikoranabuhanga rya Biologiya:
NAD ikoreshwa mu buryo butandukanye bwa biotechnological, harimo culture y'uturemangingo, fermentation, na enzyme engineering. Ikora nk'ikintu cy'ingenzi mu mikorere myinshi ya enzymes n'inzira za metabolism, bigatuma igira akamaro mu gutunganya bioprocessing no gukora biomanufacturing.
Ubushakashatsi n'Iterambere:
NAD ikoreshwa nk'igikoresho cy'ubushakashatsi muri laboratwari z'amashuri n'inganda mu kwiga imikorere y'uturemangingo, umusaruro w'ingufu, n'inyungu zishobora kubaho ku buzima zijyanye no guhinduranya NAD. Ni ingingo ikorerwaho ubushakashatsi bwa siyansi ku ngaruka zayo mu gusaza, indwara za metabolic, n'indwara zo kwangirika kw'imitsi.
Ibikoresho byo mu rwego rwo hejuru:
NAD ishyirwa mu bikoresho byo kwita ku ruhu no kwisiga kubera ubushobozi bwayo bwo gushyigikira ubuzima bw'uturemangingo n'ubuzima bwatwo. Igurishwa nk'ikintu gifite ubushobozi bwo kurwanya gusaza no kuvugurura uburumbuke.
Indabo yacu ikomoka ku bimera ikorwa hakoreshejwe ingamba zikomeye zo kugenzura ubuziranenge kandi ikurikiza amahame yo hejuru y’uburyo bwo gukora. Dushyira imbere umutekano n’ubwiza bw’ibicuruzwa byacu, tukareba ko byujuje ibisabwa n’amategeko n’ibyemezo by’inganda. Uku kwiyemeza ubuziranenge kugamije gushyiraho icyizere n’icyizere mu kwizerwa kw’ibicuruzwa byacu. Uburyo rusange bwo kubitunganya ni ubu bukurikira:
Kubika: Bika ahantu hakonje, humutse kandi hasukuye, Urinde ubushuhe n'urumuri rutaziguye.
Ipaki nini: 25kg/ingoma.
Igihe cyo gutanga serivisi: Iminsi 7 nyuma yo gutumiza.
Igihe cyo kuruhuka: Imyaka 2.
Icyitonderwa: Ibisobanuro byihariye nabyo birashobora kugerwaho.
25kg/agasanduku
Gupfunyika by'imbaraga
Umutekano w'ibikoresho
Ikoranabuhanga rigezweho
munsi ya 100kg, iminsi 3-5
Serivisi yo ku nzu n'inzu biroroshye gufata ibicuruzwa
Ku nkengero z'inyanja
Birenze 300kg, hafi iminsi 30
Hakenewe umuhuzabikorwa w'inzobere mu gutanga serivisi zo ku cyambu uvuye ku cyambu
Mu ndege
100kg-1000kg, iminsi 5-7
Hakenewe umuhuzabikorwa w'inzobere mu gutanga serivisi zo ku kibuga cy'indege kuva ku kibuga cy'indege kugeza ku kibuga cy'indege
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