Ifu karemano ya Camptothecin (CPT)
Ifu y’umukara ya Camptothecin (CPT) ni ikintu gikomoka ku giti cya Camptotheca acuminata, kizwi kandi ku izina rya "igiti cy’ibyishimo" cyangwa "igiti cy’ubuzima." Ni alkaloid isanzwe yagaragaye ko ifite ubushobozi bwo kurwanya kanseri. Camptothecin n’ibiyikomokaho byakoreweho ubushakashatsi kugira ngo bishobore gukoreshwa mu kuvura kanseri, kuko byagaragaye ko bibuza gukura kw’uturemangingo twa kanseri binyuze mu kubangamira imikorere ya enzyme yitwa topoisomerase I. Uku guhungabana gushobora kwangiza ADN ndetse no gupfa kw’uturemangingo mu turemangingo twa kanseri. Ifu y’umukara ya Camptothecin irimo gukorwaho ubushakashatsi ku bushobozi bwayo nk’umuti wa chimiotherapie kandi ni ingenzi ku nganda zikora imiti mu guteza imbere imiti irwanya kanseri. Kubindi bisobanuro ntutindiganye kuvugana nagrace@email.com.
| Izina ry'igicuruzwa | Camptotecin |
| Izina ry'Ikilatini | Camptotheca Acuminata |
| Irindi zina | Camptotecin 98% |
| Igice cyakoreshejwe | Imbuto |
| Ibisobanuro | 98% |
| Uburyo bwo Gupima | HPLC |
| Isura | Ifu y'urushinge rw'umuhondo woroshye |
| Nimero ya CAS | 7689/3/4 |
| Ifurumu ya Mol. | C20H16N2O4 |
| Uburemere bwa Mol. | 348.35 |
| Igihe cyo Kubika | Imyaka 2 |
| Ikintu | Ikizamini Sgahunda | Isuzuma Rigisubizo | |
| Isura | Ifu | Amategeko n'amabwiriza | |
| Ibara | Ifu y'umuhondo woroshye | Amategeko n'amabwiriza | |
| Ingano y'uduce duto | 100% pass 80 mesh | Amategeko n'amabwiriza | |
| Oder | Ibiranga | Amategeko n'amabwiriza | |
| Uburyohe | Ibiranga | Amategeko n'amabwiriza | |
| Igihombo mu kumisha | ≤5.0% | 2.20% | |
| Ibisigazwa biri mu gucana | ≤0.1% | 0.05% | |
| Asetone isigaye | ≤0.1% | Amategeko n'amabwiriza | |
| Ethanol isigaye | ≤0.5% | Amategeko n'amabwiriza | |
| Heave Metals | ≤10ppm | Amategeko n'amabwiriza | |
| Na | ≤0.1% | <0.1% | |
| Pb | ≤3 ppm | Amategeko n'amabwiriza | |
| Isahani yose | <1000CFU/g | Amategeko n'amabwiriza | |
| Umusemburo n'Ibihumyo | <100 CFU /g | Amategeko n'amabwiriza | |
| E. Coli | Ububi | Amategeko n'amabwiriza | |
| Salmonella | Ububi | Amategeko n'amabwiriza | |
| Umwanzuro: Huza na USP Standard | |||
Camptothecin ni ikinyabutabire gifite akamaro kanini mu buvuzi. Ibiranga iki gicuruzwa birimo:
Ubwiza buhanitse:Ibicuruzwa bya Camptothecin ubusanzwe bifite isuku nyinshi, bigatuma bikora neza kandi bikagira umutekano mu ikorwa ry’imiti.
Imiterere yo kurwanya kanseri:Camptothecin yakozweho ubushakashatsi bwinshi kandi ikoreshwa mu bijyanye n'imiti irwanya kanseri kandi ifite ubushobozi bwo kurwanya kanseri. Kubwibyo, kimwe mu bintu biyiranga ni ubushobozi bwayo bwo kurwanya kanseri.
Inkomoko karemano:Bimwe mu bicuruzwa bya camptothecin bivanwa mu bimera karemano bityo bikaba bikwiye gukoreshwa mu gukora ibikomoka ku bimera karemano n'ibikomoka ku bimera karemano.
Icyiciro cy'imiti:Ibicuruzwa bya Camptothecin ubusanzwe byujuje ibisabwa mu rwego rw'imiti kandi birakwiriye gukoreshwa mu gutegura imiti mu nganda zikora imiti.
Porogaramu zifite imikorere myinshi:Ibicuruzwa bya Camptothecin bishobora gukoreshwa mu bushakashatsi no mu iterambere ry’imiti, mu gutegura imiti, mu bicuruzwa by’ubuzima karemano, no mu bindi bice, kandi bifite amahirwe menshi yo kubikoresha.
Icyitonderwa ni uko camptothecin n'ibicuruzwa byayo bigomba gukurikiza amabwiriza ajyanye n'ibyo n'uburyo bwo kuyikoresha mu mutekano.
Ifu karemano ya camptothecin, ifite nibura 98% by'ubuziranenge, ifitanye isano n'inyungu nyinshi zishobora kubaho ku buzima, zirimo:
Imiterere yo kurwanya kanseri:Camptothecin izwiho ubushobozi bwayo bwo kurwanya kanseri. Ibuza imikorere ya enzyme topoisomerase I, igira uruhare mu kongera gukora ADN no gutandukanya uturemangingo, bigatuma iba ikintu cy'agaciro mu kuvura kanseri no gukora ubushakashatsi.
Igikorwa cyo kurwanya ogisijeni:Camptothecin ifite ubushobozi bwo kurwanya okisidasiyo, ishobora gufasha mu kugabanya stress ya okisidasiyo no kurwanya radicals zidafite akamaro mu mubiri, bikaba byagira uruhare mu buzima bwiza no mu mibereho myiza muri rusange.
Ingaruka zo kurwanya ububyimbirwe:Ubushakashatsi bumwe na bumwe bwerekana ko camptothecin ishobora kugira ingaruka ku bubyimbirwe, ibyo bikaba byagira akamaro mu kuvura indwara z’ububyimbirwe n’ibimenyetso bifitanye isano na zo.
Ingaruka zishobora guterwa no kurinda ubwonko:Hari ubushakashatsi burimo gukorwa bwerekana ko camptothecin ishobora kugira ubushobozi bwo kurinda ubwonko, ibyo bikaba bishobora kugira akamaro mu bijyanye n'indwara zo kwangirika kw'ubwonko ndetse n'ubuzima bw'ubwonko.
Ni ngombwa kumenya ko nubwo ifu karemano ya camptothecin ishobora gutanga inyungu ku buzima, ikoreshwa ryayo n'ikoreshwa ryayo bigomba kwitabwaho cyane, kandi ni ngombwa kugisha inama abaganga mbere yo kuyikoresha mu bikorwa bimwe na bimwe bifitanye isano n'ubuzima.
Ifu karemano ya camptothecin ifite nibura 98% by'ubuziranenge ifite ubushobozi butandukanye mu bijyanye n'imiti, intungamubiri, n'ubushakashatsi. Zimwe mu ngamba zirambuye zirimo:
Ubushakashatsi ku ndwara ya kanseri n'iterambere ry'imiti:Camptothecin yigwa cyane kubera imiterere yayo yo kurwanya kanseri. Ifu ishobora gukoreshwa muri laboratwari z'ubushakashatsi mu kwiga ibinyabuzima bya kanseri, iterambere ry'imiti, no gukora imiti irwanya kanseri.
Imiti: Imiti:Ifu karemano ya camptothecin ishobora gukoreshwa mu gukora imiti, nk'imiti iterwa mu nganda, imiti inyobwa, cyangwa uduce duto two mu bwoko bwa transdermal mu kuvura ubwoko bumwe na bumwe bwa kanseri.
Ibikoresho by'intungamubiri:Ifu ishobora gushyirwa mu bikomoka ku ntungamubiri, nk'inyongeramusaruro, bigamije gutanga inyungu zishobora kubaho ku buzima zijyanye n'ubushobozi bwayo bwo kurwanya ubushyuhe n'ubudahangarwa bw'umubiri.
Porogaramu zo mu rwego rwo kwisiga:Camptothecin ishobora gukoreshwa mu guteza imbere ibikoresho byo kwisiga, nk'amavuta yo kurwanya gusaza cyangwa serum, bitewe n'ubushobozi bwayo bwo kurwanya antioxydant no kurinda uruhu.
Ubushakashatsi n'Iterambere:Ifu karemano ya camptothecin ishobora gukoreshwa nk'igikoresho cy'ubushakashatsi mu bushakashatsi butandukanye bwa siyansi bujyanye na kanseri, ubuvuzi bw'imiti, n'ubutabire bw'imiti.
Ni ngombwa kumenya ko ikoreshwa rya camptothecin mu buryo ubwo aribwo bwose rigomba kuba rikurikije amabwiriza agenga imiti kandi rigakurikiranwa n'inzobere zibifitiye ubushobozi bitewe n'ubushobozi bwayo bukomeye mu by'imiti.
Ifu karemano ya camptothecin, ifite imiterere ikomeye mu by'imiti, ishobora kugira ingaruka mbi, cyane cyane iyo ikoreshejwe nabi cyangwa idakurikiranwe neza na muganga. Zimwe mu ngaruka mbi zishobora kuba zirimo:
Uburozi:Camptothecin izwiho kugira ingaruka mbi, cyane cyane iyo ikoreshejwe ku rugero rwo hejuru. Ishobora kwangiza uturemangingo dusanzwe hamwe n’uturemangingo twa kanseri, bigatera ingaruka mbi ku ngingo zitandukanye n’imitsi.
Ihungabana ry'igifu:Kurya camptothecin cyangwa ibindi bikomoka kuri yo bishobora gutera ibibazo byo mu gifu nko kugira isesemi, kuruka, impiswi no kubabara mu nda.
Ingaruka z'amaraso:Camptothecin ishobora kugira ingaruka ku ikorwa ry'uturemangingo tw'amaraso, bigatera indwara nka anemia, leukopenia, cyangwa thrombocytopenia.
Uburyo uruhu rumererwa neza:Gukorana na camptothecin cyangwa imiti yayo bishobora gutera uburyaryate bw'uruhu cyangwa allergie kuri bamwe mu bantu.
Izindi ngaruka zishobora kubaho:Izindi ngaruka zishobora kubaho zishobora kuba zirimo gutakaza umusatsi, umunaniro, intege nke, no kugabanya ubudahangarwa bw'umubiri.
Ni ngombwa gushimangira ko ikoreshwa ry'ifu karemano ya camptothecin rigomba kuyoborwa n'inzobere mu by'ubuzima, cyane cyane abaganga b'inzobere mu ndwara za kanseri cyangwa abahanga mu by'imiti, bitewe n'ingaruka zayo zikomeye mu by'imiti ndetse n'uburozi bushobora kubaho. Byongeye kandi, abantu bagomba kumenya amabwiriza agenga imicungire n'uburyo bwo kwirinda indwara zijyanye no gufata no gukoresha camptothecin n'ibindi biyikomokaho.
Gupakira no Gutanga Serivisi
Gupfunyika
* Igihe cyo gutanga: Hafi iminsi 3-5 y'akazi nyuma yo kwishyura.
* Ipaki: Mu ngoma za fibre hamwe n'imifuka ibiri ya pulasitiki imbere.
* Uburemere rusange: 25kgs/ingoma, Uburemere rusange: 28kgs/ingoma
* Ingano y'ingoma n'ingano yayo: ID42cm × H52cm, 0.08 m³/ Ngoma
* Kubika: Bibikwa ahantu humutse kandi hakonje, bikarinda urumuri rwinshi n'ubushyuhe bwinshi.
* Igihe cyo kubika: Imyaka ibiri iyo bibitswe neza.
Kohereza
* DHL Express, FEDEX, na EMS ku ngano iri munsi ya 50KG, ubusanzwe yitwa serivisi ya DDU.
* Kohereza mu mazi ku bilo zirenga 500; kandi kohereza mu kirere ku bilo 50 biri hejuru.
* Ku bicuruzwa bifite agaciro kanini, nyamuneka hitamo kohereza mu kirere na DHL express kugira ngo ugire umutekano.
* Nyamuneka menya niba ushobora gutanga uruhushya igihe ibicuruzwa bigeze kuri gasutamo yawe mbere yo gutanga komande. Ku baguzi baturutse muri Megizike, Turukiya, Ubutaliyani, Rumaniya, Uburusiya, n'ahandi hantu hatandukanye.
Uburyo bwo kwishyura no gutanga
Ikoranabuhanga rigezweho
munsi ya 100kg, iminsi 3-5
Serivisi yo ku nzu n'inzu biroroshye gufata ibicuruzwa
Ku nkengero z'inyanja
Birenze 300kg, hafi iminsi 30
Hakenewe umuhuzabikorwa w'inzobere mu gutanga serivisi zo ku cyambu uvuye ku cyambu
Mu ndege
100kg-1000kg, iminsi 5-7
Hakenewe umuhuzabikorwa w'inzobere mu gutanga serivisi zo ku kibuga cy'indege kuva ku kibuga cy'indege kugeza ku kibuga cy'indege
Ibisobanuro by'umusaruro (Imbonerahamwe y'ibikorwa)
1. Gushaka no gusarura
2. Gukuramo
3. Kwibanda ku bintu no kubitunganya
4. Kumisha
5. Gushyira mu bikorwa ibipimo ngenderwaho
6. Igenzura ry'Ubuziranenge
7. Gupakira 8. Gukwirakwiza
Icyemezo
It byemejwe n'ibyemezo bya ISO, HALAL, na KOSHER.
