Ifu ya Kamptothecine Kamere (CPT)
Ifu ya camptothecine isanzwe (CPT) ni uruvange rukomoka ku giti cya Camptotheca acuminata, kizwi kandi ku izina rya “igiti cyiza” cyangwa “igiti cy'ubuzima.” Nibisanzwe alkaloide igaragara ko ifite imiti irwanya kanseri. Camptothecin n'ibiyikomokaho byakozweho ubushakashatsi ku buryo bushobora gukoreshwa mu kuvura kanseri, kuko byagaragaye ko bibuza ikura ry'uturemangingo twa kanseri kubangamira imikorere ya enzyme yitwa topoisomerase I. Uku guhungabana gushobora kwangiza ADN hanyuma amaherezo agapfa. muri kanseri. Ifu ya camptothecine isanzwe irimo gukorwaho ubushakashatsi kubushobozi bwayo nka chimiotherapie kandi ishishikajwe ninganda zimiti kugirango habeho imiti irwanya kanseri. Kubindi bisobanuro ntutindiganye kuvugana nabograce@email.com.
| Izina ryibicuruzwa | Kamptothecin |
| Izina ry'ikilatini | Kamptotheca Acuminata |
| Irindi zina | Camptothecin 98% |
| Igice Cyakoreshejwe | Imbuto |
| Ibisobanuro | 98% |
| Uburyo bwo Kwipimisha | HPLC |
| Kugaragara | Ifu yumuhondo yoroheje yumuhondo |
| URUBANZA No. | 7689/3/4 |
| Mol. Inzira | C20H16N2O4 |
| Mol. Ibiro | 348.35 |
| Ubuzima bwa Shelf | Imyaka 2 |
| Ingingo | Ikizamini S.tandard | Ikizamini R.esult | |
| Kugaragara | Ifu | Bikubiyemo | |
| Ibara | Ifu yumuhondo yoroheje | Bikubiyemo | |
| Ingano ya Particle | 100% batsinze mesh 80 | Bikubiyemo | |
| Oder | Ibiranga | Bikubiyemo | |
| Biryohe | Ibiranga | Bikubiyemo | |
| Gutakaza Kuma | ≤5.0% | 2.20% | |
| Ibisigisigi kuri Ignition | ≤0.1% | 0,05% | |
| Asetone isigaye | ≤0.1% | Bikubiyemo | |
| Ethanol isigaye | ≤0.5% | Bikubiyemo | |
| Heave Metals | ≤10ppm | Bikubiyemo | |
| Na | ≤0.1% | <0.1% | |
| Pb | ≤3 ppm | Bikubiyemo | |
| Isahani yuzuye | <1000CFU / g | Bikubiyemo | |
| Umusemburo & Mold | <100 CFU / g | Bikubiyemo | |
| E. Coli | Ibibi | Bikubiyemo | |
| Salmonella | Ibibi | Bikubiyemo | |
| Umwanzuro: Huza na USP Standard | |||
Camptothecin nuruvange rufite agaciro gakomeye kubuvuzi. Ibicuruzwa byayo biranga:
Isuku ryinshi:Ibicuruzwa bya Camptothecine mubisanzwe bifite isuku nyinshi, byemeza imikorere yabyo n'umutekano mugutezimbere ibiyobyabwenge no kubibyaza umusaruro.
Kurwanya kanseri:Camptothecin yizwe cyane kandi ikoreshwa mubijyanye n'imiti irwanya kanseri kandi ifite ibikorwa byo kurwanya ibibyimba. Kubwibyo, kimwe mubicuruzwa biranga ubushobozi bwacyo bwo kurwanya kanseri.
Inkomoko karemano:Ibicuruzwa bimwe na bimwe bya camptothecine bivanwa mubihingwa karemano bityo bikwiriye gukoreshwa mugukora ibicuruzwa bisanzwe nibinyabuzima.
Urwego rwa farumasi:Ibicuruzwa bya Camptothecine mubisanzwe byujuje ubuziranenge bwa farumasi kandi birakwiriye gukoreshwa mubitegura imiti munganda zimiti.
Porogaramu nyinshi zikora:Ibicuruzwa bya Camptothecine birashobora gukoreshwa mubushakashatsi bwibiyobyabwenge niterambere, gutegura imiti, ibikomoka ku buzima karemano, nizindi nzego, kandi bifite ibyifuzo byinshi.
Twabibutsa ko camptothecin nibicuruzwa byayo bigomba gukurikiza byimazeyo amabwiriza abigenga hamwe nuburyo bukoreshwa neza mugihe cyo kuyakoresha.
Ifu ya camptothecine isanzwe, ifite byibuze 98% byera, ifitanye isano nibyiza byinshi byubuzima, harimo:
Anticancer Ibiranga:Camptothecin izwiho kuba ifite anticancer ikomeye. Irabuza ibikorwa bya enzyme topoisomerase ya I, igira uruhare mu kwigana ADN no kugabana selile, ikagira uruhare runini mu kuvura kanseri no mu bushakashatsi.
Igikorwa cya Antioxydeant:Camptothecin yerekana antioxydeant, ishobora gufasha mukugabanya stress ya okiside no kurwanya radicals yubusa mumubiri, bikaba byagira uruhare mubuzima rusange no kumererwa neza.
Ingaruka zo kurwanya inflammatory:Ubushakashatsi bumwe bwerekana ko camptothecine ishobora kugira ingaruka zo kurwanya inflammatory, zishobora kuba ingirakamaro mugukemura ibibazo byumuriro nibimenyetso bifitanye isano nayo.
Ingaruka zishobora kuba Neuroprotective:Hariho ubushakashatsi bugaragara bwerekana ko camptothecine ishobora kuba ifite imitekerereze ya neuroprotective, ishobora kuba ingirakamaro mubijyanye n'indwara zifata ubwonko n'ubuzima bw'ubwonko.
Ni ngombwa kumenya ko mugihe ifu ya camptothecine isanzwe ishobora gutanga inyungu zubuzima, imikoreshereze yayo nogukoresha bigomba gutekerezwa neza, kandi ni ngombwa kugisha inama inzobere mubuzima mbere yo kuyikoresha mubikorwa runaka bijyanye nubuzima.
Ifu ya camptothecine isanzwe ifite byibura 98% byera bifite uburyo butandukanye bushobora gukoreshwa mubijyanye na farumasi, intungamubiri, nubushakashatsi. Porogaramu zirambuye zirimo:
Ubushakashatsi bwa Kanseri no guteza imbere ibiyobyabwenge:Camptothecin yizwe cyane kubijyanye na anticancer. Ifu irashobora gukoreshwa muri laboratoire yubushakashatsi mu kwiga ibinyabuzima bya kanseri, iterambere ry’ibiyobyabwenge, no gukora imiti igabanya ubukana.
Imiti ya farumasi:Ifu ya camptothecine isanzwe irashobora gukoreshwa mugutezimbere imiti, nkibisubizo byatewe inshinge, imiti yo mu kanwa, cyangwa imiti ya transdermal yo kuvura ubwoko bumwe na bumwe bwa kanseri.
Ibitunga umubiri:Ifu irashobora kwinjizwa mubicuruzwa byintungamubiri, nkibiryo byongera ibiryo, bigamije gutanga inyungu zubuzima zijyanye na antioxydeant na anti-inflammatory.
Ikoreshwa rya Cosmeceutical Porogaramu:Camptothecine irashobora gukoreshwa mugutezimbere ibicuruzwa biva mu kirere, nk'amavuta yo kurwanya gusaza cyangwa serumu, bitewe na antioxydants kandi irinda uruhu.
Ubushakashatsi n'Iterambere:Ifu ya camptothecine isanzwe irashobora gukoreshwa nkigikoresho cyubushakashatsi mubushakashatsi butandukanye bwa siyanse bujyanye na kanseri, farumasi, na chimie chimique.
Ni ngombwa kumenya ko ikoreshwa rya camptothecine mubisabwa byose bigomba kuba byubahiriza amabwiriza ngenderwaho kandi bikagenzurwa ninzobere zibishoboye kubera imiti ya farumasi ikomeye.
Ifu ya camptothecine isanzwe, hamwe nubuhanga bukomeye bwa farumasi, irashobora kugira ingaruka mbi, cyane cyane iyo ikoreshejwe nabi cyangwa idakurikiranwa neza. Ingaruka zimwe zishobora kuba zirimo:
Uburozi:Camptothecin izwiho kugira ingaruka z'uburozi, cyane cyane kuri dosiye nyinshi. Irashobora kwangiza ingirabuzimafatizo zisanzwe hamwe na kanseri ya kanseri, biganisha ku ngaruka mbi ku ngingo zitandukanye.
Guhagarika Gastrointestinal:Kwinjiza camptothecine cyangwa ibiyikomokaho bishobora gutera ibibazo byo munda nko kugira isesemi, kuruka, impiswi, no kubabara mu nda.
Ingaruka zo kuvura indwara:Camptothecine irashobora kugira ingaruka kumusemburo wamaraso, biganisha kumiterere nka anemia, leukopenia, cyangwa trombocytopenia.
Kumva uruhu:Guhura neza na camptothecin cyangwa ibisubizo byayo birashobora gutera uburibwe bwuruhu cyangwa reaction ya allergique kubantu bamwe.
Izindi ngaruka zishoboka:Izindi ngaruka zishobora kuba zirimo gutakaza umusatsi, umunaniro, intege nke, hamwe na immunosuppression.
Ni ngombwa gushimangira ko gukoresha ifu ya camptothecine isanzwe igomba kuba iyobowe ninzobere mu buvuzi, cyane cyane abahanga mu bya oncologue cyangwa abafarumasiye, bitewe n’ingaruka zikomeye za farumasi n’uburozi bushobora kuba. Byongeye kandi, abantu ku giti cyabo bagomba kumenya amabwiriza ngenderwaho hamwe nuburyo bwo kwirinda umutekano bujyanye no gufata no gukoresha camptothecine n'ibiyikomokaho.
Gupakira na serivisi
Gupakira
* Igihe cyo Gutanga: Hafi y'iminsi 3-5 y'akazi nyuma yo kwishyura.
* Ipaki: Mu ngoma ya fibre ifite imifuka ibiri ya plastike imbere.
* Uburemere bwuzuye: 25kgs / ingoma, Uburemere rusange: 28kgs / Ingoma
* Ingano yingoma & Umubumbe: ID42cm × H52cm, 0.08 m³ / Ingoma
* Ububiko: Ubitswe ahantu humye kandi hakonje, irinde urumuri rukomeye nubushyuhe.
* Ubuzima bwa Shelf: Imyaka ibiri iyo ibitswe neza.
Kohereza
* DHL Express, FEDEX, na EMS kumubare uri munsi ya 50KG, mubisanzwe bita serivisi ya DDU.
* Kohereza inyanja kurenza kg 500; no kohereza mu kirere birahari kuri kg 50 hejuru.
* Kubicuruzwa bifite agaciro kanini, nyamuneka hitamo kohereza ikirere hamwe na DHL Express kubwumutekano.
* Nyamuneka wemeze niba ushobora gukora ibicuruzwa mugihe ibicuruzwa bigeze kuri gasutamo mbere yo gutanga itegeko. Ku baguzi baturutse muri Mexico, Turukiya, Ubutaliyani, Rumaniya, Uburusiya, n'utundi turere twa kure.
Uburyo bwo Kwishura no Gutanga
Express
Munsi ya 100kg, Iminsi 3-5
Serivisi ku muryango byoroshye gufata ibicuruzwa
Ku nyanja
Kurenga 300 kg, Hafi Iminsi 30
Icyambu kugeza ku cyambu serivisi yumwuga yemewe arakenewe
Na Air
100kg-1000kg, Iminsi 5-7
Ikibuga cyindege cya serivise yikibuga cyumwuga gikenewe
Ibisobanuro birambuye ku musaruro (Imbonerahamwe yerekana)
1. Gushakisha no Gusarura
2. Gukuramo
3. Kwibanda no kwezwa
4. Kuma
5. Ibipimo ngenderwaho
6. Kugenzura ubuziranenge
7. Gupakira 8. Gukwirakwiza
Icyemezo
It byemejwe na ISO, HALAL, na KOSHER ibyemezo.
