Ifu ya Rotundine (l-tetrahydropalmatine, l-THP)

Rotundine, izwi kandi nka l-tetrahydropalmatine (l-THP), ni ikinyabutabire gifite imiterere y’imiti igira ingaruka ku mitsi yo mu mutwe no ku mitsi y’umutima. Byavuzwe ko ifite ingaruka zo kugabanya ububabare, gutuza, gushyuha no guhangayika. Byongeye kandi, byagaragaye ko ifite ingaruka zo kurinda indwara zo mu bwonko no mu mitsi yangiritse. Rotundine izwiho kandi ubushobozi bwayo bwo gusubiza inyuma ubudahangarwa bw’imiti myinshi mu turemangingo twa kanseri ndetse n’imiterere yayo yo kubuza imiyoboro ya kalisiyumu.
Ishobora kuboneka mu bijumba bya Stephania tetrandra na Corydalis yanhusuo, cyangwa hakoreshejwe uburyo bwo gukora imiti. Ikorwa muri tetrahydropalmatine binyuze mu kugabanya, gucikamo ibice, no gukora alkali. Tetrahydropalmatine ifite iyode ishobora gukorwa muri tetrahydropalmatine binyuze mu gukora alkali na oxidation kugira ngo ikorerwemo.
Ku bijyanye n'imiti, Rotundine yinjizwa neza nyuma yo kuyinywa mu kanwa, kandi ikwirakwira cyane cyane mu mavuta, hagakurikiraho ibihaha, umwijima n'impyiko. Isohoka cyane cyane mu mpyiko. Ubushakashatsi bwakozwe ku mbeba n'urukwavu bwagaragaje ko Rotundine ishobora kwinjira mu ruzitiro rw'amaraso n'ubwonko ikagera mu bwonko, aho ubwinshi bw'amaraso mu bwonko buri hasi ugereranyije n'ubwinshi bw'amaraso nyuma y'amasaha 2.
Ku ngaruka mbi, Rotundine ishobora gutera gusinzira, isereri, umunaniro, isesemi, ndetse rimwe na rimwe no guhungabana kw'ubwivumbure. Amabwiriza yo kwirinda arimo kwirinda kuyikoresha ku bagore batwite n'abonsa, kumenya ko ishobora kwihanganira kuyikoresha igihe kirekire, no kwitonda mu gihe ufata hamwe n'imiti igabanya ubukana bw'imitsi yo mu mutwe, hamwe no gukosora urugero rw'umuti mu gihe bibaye ngombwa.
Muri make, Rotundine ni ikinyabutabire gifite ingaruka zitandukanye ku miti, kandi imiterere yayo ituma ishishikarizwa mu bushakashatsi butandukanye, burimo kuvura ububabare, ubuzima bw'umutima n'imitsi, ndetse no kuvura kanseri. Kubindi bisobanuro hamagara.grace@biowaycn.com.