Vinca Rosea Gukuramo Vincristine
Vinca Rosea Ikuramo Vincristine bivuga uruganda rukora imiti Vincristine, rukomoka ku gihingwa cya periwinkle (Vinca rosea), kizwi kandi ku izina rya Catharanthus rose, amaso meza, Cape periwinkle, igihingwa cy’imva, Madagasikari periwinkle, umuja ushaje, periwinkle, roza periwinkle, ni ubwoko bwibimera byindabyo mumuryango Apocynaceae.
Vincristine ni alkaloide isanzwe kandi ikoreshwa nk'imiti ya chimiotherapie mu kuvura ubwoko butandukanye bwa kanseri, harimo na leukemia, lymphoma, n'ibibyimba bikomeye. Ikora mu guhagarika imikurire ya selile.
| Ibyingenzi byingenzi mubushinwa | Izina ry'icyongereza | URUBANZA No. | Uburemere bwa molekile | Inzira ya molekulari |
| 长春胺 | Vincamine | 1617-90-9 | 354.44 | C21H26N2O3 |
| 脱水长春碱 | Anhydrovinblastine | 38390-45-3 | 792.96 | C46H56N4O8 |
| 異長春花苷內酰胺 | Strictosamide | 23141-25-5 | 498.53 | C26H30N2O8 |
| 四氢鸭脚木碱 | Tetrahydroalstonine | 6474-90-4 | 352.43 | C21H24N2O3 |
| 酒石酸长春瑞滨 | Vinorelbine Tartrate | 125317-39-7 | 1079.12 | C45H54N4O8.2 (C4H6O6); C. |
| 长春瑞滨 | Vinorelbine | 71486-22-1 | 778.93 | C45H54N4O8 |
| 长春新碱 | Vincristine | 57-22-7 | 824.96 | C46H56N4O10 |
| 硫酸长春新碱 | Vincristine sulfate | 2068-78-2 | 923.04 | C46H58N4O14S |
| 硫酸长春质碱 | Catharanthine Sulfate | 70674-90-7 | 434.51 | C21H26N2O6S |
| 酒石酸长春质碱 | Catharanthine hemitartrate | 4168-17-6 | 486.51 | C21H24N2O2.C4H6O6 |
| 长春花碱 | Vinblastine | 865-21-4 | 810.99 | C46H58N4O9 |
| 长春质碱 | Catharanthine | 2468-21-5 | 336.43 | C21H24N2O2 |
| 文朵灵 | Vindoline | 2182-14-1 | 456.53 | C25H32N2O6 |
| 硫酸长春碱 | Vinblastine Sulfate | 143-67-9 | 909.05 | C46H60N4O13S |
| β- 谷甾醇 | Sitosterol | 83-46-5 | 414.71 | C29H50O |
| 菜油甾醇 | Campesterol | 474-62-4 | 400.68 | C28H48O |
| 齐墩果酸 | Acide Oleanolike | 508-02-1 | 456.7 | C30H48O3 |
| UMWIHARIKO W'ibicuruzwa | ||
| Izina ry'ibicuruzwa: | Vinca rose | |
| Izina ryibimera: | Catharanthus rose (L.) | |
| Igice c'ibimera | Indabyo | |
| Igihugu bakomokamo: | Ubushinwa | |
| GUSESENGURA INGINGO | UMWIHARIKO | UBURYO BWO GUKORA IKIZAMINI |
| Kugaragara | Ifu nziza | Organoleptic |
| Ibara | Ifu nziza | Biboneka |
| Impumuro & uburyohe | Ibiranga | Organoleptic |
| Kumenyekanisha | Bisa na RS icyitegererezo | HPTLC |
| Gukuramo Ikigereranyo | 4: 1 ~ 20: 1; Vincristine 98% min | |
| Isesengura | 100% kugeza kuri 80 mesh | USP39 <786> |
| Gutakaza kumisha | ≤ 5.0% | Amayero.Ph.9.0 [2.5.12] |
| Ivu | ≤ 5.0% | Uburayi.Ph.9.0 [2.4.16] |
| Kurongora (Pb) | ≤ 3.0 mg / kg | Uburayi.Ph.9.0 <2.2.58> ICP-MS |
| Arsenic (As) | ≤ 1.0 mg / kg | Uburayi.Ph.9.0 <2.2.58> ICP-MS |
| Cadmium (Cd) | ≤ 1.0 mg / kg | Uburayi.Ph.9.0 <2.2.58> ICP-MS |
| Mercure (Hg) | ≤ 0.1 mg / kg -Reg.EC629 / 2008 | Uburayi.Ph.9.0 <2.2.58> ICP-MS |
| Icyuma kiremereye | ≤ 10.0 mg / kg | Uburayi.Ph.9.0 <2.4.8> |
| Ibisigisigi | Hindura Eur.ph. 9.0 <5,4> na EC Amabwiriza yu Burayi 2009/32 | Uburayi.Ph.9.0 <2.4.24> |
| Ibisigisigi byica udukoko | Hindura Amabwiriza (EC) No.396 / 2005 harimo imigereka namakuru agezweho Reg.2008 / 839 / CE | Gas Chromatography |
| Bagiteri zo mu kirere (TAMC) | 0010000 cfu / g | USP39 <61> |
| Umusemburo / Ibishushanyo (TAMC) | 0001000 cfu / g | USP39 <61> |
| Escherichia coli: | Kubura muri 1g | USP39 <62> |
| Salmonella spp: | Kubura muri 25g | USP39 <62> |
| Staphylococcus aureus: | Kubura muri 1g | |
| Listeria Monocytogenens | Kubura muri 25g | |
| Aflatoxins B1 | ≤ 5 ppb -Reg.EC 1881/2006 | USP39 <62> |
| Aflatoxine ∑ B1, B2, G1, G2 | ≤ 10 ppb -Reg.EC 1881/2006 | USP39 <62> |
Ibicuruzwa biranga Vinca Rosea Gukuramo Vincristine irashobora kubamo:
Isuku ryinshi:Ibicuruzwa bya Vincristine mubisanzwe bifite isuku nyinshi kandi byubahiriza amahame akomeye yo gukora ibiyobyabwenge kugirango ibiyobyabwenge bisukure kandi bihamye.
Inkomoko y'inkomoko:Ubusanzwe Vincristine ikurwa mu gihingwa cya Catharanthus. Umusaruro wacyo urakurikiranwa kandi uhuza no gukusanya no gutanga umusaruro wibikoresho bivura ibihingwa.
Imiti ihamye:Nka alkaloide ivanze, vincristine ifite imiti ihamye kandi ikwiranye no gukora imiti no kubika igihe kirekire.
Igikorwa cyo kurwanya ibibyimba:Nkumuti urwanya ibibyimba, vincristine ifite ibikorwa byo kubuza gukura no gukwirakwira kwingirabuzimafatizo kandi ikwiriye kuvura kanseri zitandukanye.
Kugenzura ivuriro:Vincristine yagenzuwe mubuvuzi kandi ikoreshwa cyane mubikorwa byubuvuzi, hifashishijwe amakuru yizewe ya farumasi nubuvuzi.
Ibiranga ibicuruzwa byerekana ubuziranenge, ibikorwa, n’agaciro ka vincristine nkumuti wingenzi urwanya kanseri.
Vinca Rosea Ikuramo Vincristine izwi cyane cyane mubikorwa bya farumasi mukuvura kanseri kandi ntabwo isanzwe ifitanye isano nubuzima butaziguye kubukoresha muri rusange. Vincristine, ikomoka ku gihingwa cya Vinca rosea, ni imiti ikomeye ya chimiotherapie ikoreshwa mu kuvura ubwoko butandukanye bwa kanseri, harimo na leukemia, lymphoma, n'ibibyimba bikomeye. Ikora ibangamira imikurire ya selile.
Ni ngombwa kumenya ko Vincristine ari imiti yandikiwe gutangwa iyobowe ninzobere mu buvuzi, kandi ikoreshwa ryayo rifitanye isano n'ingaruka zishobora guterwa n'ingaruka. Kubwibyo, ntabwo isanzwe igurishwa cyangwa ngo ikoreshwe kubuzima bwayo hanze yubuvuzi.
Ibisobanuro birambuye bya Vinca Rosea Gukuramo Vincristine harimo:
Kuvura Kanseri:Vincristine ikoreshwa cyane cyane mu kuvura ubwoko butandukanye bwa kanseri, harimo leukemia, lymphoma, n'ibibyimba bikomeye. Itangwa mubice bigize chimiotherapie kugirango ibuze imikurire ya selile.
Ubushakashatsi mu bya farumasi:Amashanyarazi akoreshwa mubushakashatsi bwa farumasi mugutezimbere uburyo bushya bwo kuvura kanseri no kwiga uburyo bukora.
Ubuvuzi bwa Shimi:Vincristine ikora nk'ingirakamaro mu bijyanye na chimie chimique, igira uruhare mu iterambere ry'imiti mishya hamwe nubuvuzi buvura.
Ikoranabuhanga mu binyabuzima:Ibikururwa birashobora gukoreshwa mubikorwa bya tekinoloji, nko gukora imiti igabanya ubukana hamwe na sisitemu yo gutanga ibiyobyabwenge.
Ibigeragezo bivura:Vincristine igira uruhare mu igeragezwa ry’amavuriro kugira ngo isuzume akamaro kayo mu kuvura kanseri zitandukanye no gukora ubushakashatsi ku bindi bikorwa by’ubuvuzi.
Gutegura ibiyobyabwenge:Amashanyarazi akoreshwa mugutegura ibicuruzwa bivura imiti, harimo ibisubizo byatewe inshinge nubundi buryo bwa dosiye yo kuvura kanseri.
Izi porogaramu zerekana uburyo butandukanye bwo gukoresha Vinca Rosea Extract Vincristine mu kuvura kanseri, ubushakashatsi mu bya farumasi, no guteza imbere ibiyobyabwenge.
Vincristine ni imiti ikomeye ya chimiotherapie, kandi kuyikoresha birashobora kuba bifitanye isano n'ingaruka nyinshi zishobora kubaho. Zimwe mu ngaruka zishobora guterwa nifu ya Vincristine irashobora kubamo:
Neurotoxicity:Vincristine irashobora kwangiza sisitemu ya nervice ya periferique, biganisha ku bimenyetso nko kunanirwa, gutitira, n'intege nke ku mpera.
Ingaruka zo munda:Ingaruka ziterwa na gastrointestinal zishobora kubamo isesemi, kuruka, kuribwa mu nda, no kubabara munda.
Kurwanya amagufwa:Vincristine irashobora guhagarika igufwa ryamagufa, bigatuma igabanuka ryumusemburo wamaraso, bishobora kuviramo kubura amaraso, kwiyongera kwandura, hamwe no kuva amaraso.
Gutakaza umusatsi:Abantu bamwe barashobora gutakaza umusatsi cyangwa kunaniza umusatsi bitewe no kuvura Vincristine.
Ububabare bw'urwasaya:Vincristine irashobora gutera ubwoko bwihariye bwububabare buzwi nka "vincristine-iterwa na neuropathie-acute-onset," irangwa no kubabara urwasaya no kumira bunguri.
Izindi ngaruka zishoboka:Ingaruka zinyongera zishobora kuba zirimo intege nke zimitsi, impinduka zumuvuduko wamaraso, hamwe na allergique.
Ni ngombwa kumenya ko urutonde rwavuzwe haruguru rutuzuye, kandi inzobere mu buvuzi zigomba gukurikiranira hafi abantu bakira Vincristine ku ngaruka zose zishobora kubaho. Ingaruka zihariye nuburemere bwazo zirashobora gutandukana kubantu. Abarwayi bagomba kuganira ku ngaruka zishobora guterwa n’ubuvuzi mbere yo gutangira kuvura Vincristine.
Gupakira na serivisi
Gupakira
* Igihe cyo Gutanga: Hafi y'iminsi 3-5 y'akazi nyuma yo kwishyura.
* Ipaki: Mu ngoma ya fibre ifite imifuka ibiri ya plastike imbere.
* Uburemere bwuzuye: 25kgs / ingoma, Uburemere rusange: 28kgs / Ingoma
* Ingano yingoma & Umubumbe: ID42cm × H52cm, 0.08 m³ / Ingoma
* Ububiko: Ubitswe ahantu humye kandi hakonje, irinde urumuri rukomeye nubushyuhe.
* Ubuzima bwa Shelf: Imyaka ibiri iyo ibitswe neza.
Kohereza
* DHL Express, FEDEX, na EMS kumubare uri munsi ya 50KG, mubisanzwe bita serivisi ya DDU.
* Kohereza inyanja kurenza kg 500; no kohereza mu kirere birahari kuri kg 50 hejuru.
* Kubicuruzwa bifite agaciro kanini, nyamuneka hitamo kohereza ikirere hamwe na DHL Express kubwumutekano.
* Nyamuneka wemeze niba ushobora gukora ibicuruzwa mugihe ibicuruzwa bigeze kuri gasutamo mbere yo gutanga itegeko. Ku baguzi baturutse muri Mexico, Turukiya, Ubutaliyani, Rumaniya, Uburusiya, n'utundi turere twa kure.
Uburyo bwo Kwishura no Gutanga
Express
Munsi ya 100kg, Iminsi 3-5
Serivisi ku muryango byoroshye gufata ibicuruzwa
Ku nyanja
Kurenga 300 kg, Hafi Iminsi 30
Icyambu kugeza ku cyambu serivisi yumwuga yemewe arakenewe
Na Air
100kg-1000kg, Iminsi 5-7
Ikibuga cyindege cya serivise yikibuga cyumwuga gikenewe
Ibisobanuro birambuye ku musaruro (Imbonerahamwe yerekana)
1. Gushakisha no Gusarura
2. Gukuramo
3. Kwibanda no kwezwa
4. Kuma
5. Ibipimo ngenderwaho
6. Kugenzura ubuziranenge
7. Gupakira 8. Gukwirakwiza
Icyemezo
It byemejwe na ISO, HALAL, na KOSHER ibyemezo.
