Ifu ya Sinomenine Hydrochloride
Sinomenine Hydrochloride ni imiti ikomoka ku gihingwa Sinomenium acutum, ikunze kuboneka muri Aziya y'Uburasirazuba. Ni alkaloide isanzwe ikoreshwa mu buvuzi bw'Ubushinwa kubera imiti irwanya inflammatory na analgesic. Ifishi ya hydrochloride ni umunyu wongera imbaraga zo gukomera no gutuza, bigatuma ukoreshwa neza muri farumasi.
Sinomenine Hydrochloride yakozweho ubushakashatsi ku ngaruka zishobora kuvura mu kuvura indwara nka rubagimpande ya rubagimpande, bitewe n'ubushobozi ifite bwo guhindura imikorere y’umubiri no kugabanya umuriro. Cyakora mukubuza umusaruro wa cytokine-pro-inflammatory hamwe nabandi bahuza bagize uruhare mugusubiza.
Usibye ingaruka zayo zo kurwanya inflammatory no analgesic, Sinomenine Hydrochloride yanagaragaje ubushobozi muri neuroprotection, anti-fibrosis, ndetse nibikorwa byo kurwanya ibibyimba mubushakashatsi butandukanye bwibanze.
Izina risanzwe ： (9a, 13a, 14a) -7,8-didehydro-4-hydroxy-3,7-dimethoxy-17-methyl-morphinan-6-imwe, monohydrochloride
CAS Umubare ： 6080-33-7
Synonyme ： Cucoline NSC 76021
Imiterere ya molekulari ： C19H23NO4 • HCl
Uburemere bwa formula ： 365.9
Isuku ： ≥98% Ikirahure gikomeye
Gukemura (Wige Ibihinduka mubisubizo)
DMF: 30 mg / ml
DMSO: 30 mg / ml
Ethanol: 5 mg / ml
PBS (pH 7.2): 5 mg / ml
Inkomoko ： Igiterwa / Sinomenium acutum
Kohereza & Ububiko Amakuru ：
Ububiko -20 ° C.
Kohereza ： Ubushyuhe bwo mucyumba
Guhagarara ： years imyaka 4
| Ingingo | Ibisobanuro | Igisubizo |
| Suzuma (HPLC) | 98.0% | 98,12% |
| Kugaragara | Ifu yera | Bikubiyemo |
| Ingano ya Particle | 98% kugeza kuri 80mesh | Bikubiyemo |
| Impumuro | Ibiranga | Bikubiyemo |
| Biryohe | Ibiranga | Bikubiyemo |
| Ibiranga umubiri | ||
| Gutakaza Kuma | ≤0.5% | 0.38% |
| Ivu | ≤0.5% | 0.46% |
| Ibyuma biremereye | ||
| Ibyuma biremereye (nka Pb) | Ibipimo bya USP (<10ppm) | <10ppm |
| Arsenic (As) | ≤2ppm | 0.78ppm |
| Kurongora (Pb) | ≤2ppm | 1.13ppm |
| Cadmium (Cd) | Plppm | 0.36ppm |
| Mercary (Hg) | ≤0.1ppm | 0.01ppm |
| Ibisigisigi byica udukoko | Kutamenyekana | Kutamenyekana |
| Umubare wuzuye | NMT 10000cfu / g | 680 cfu / g |
| Umusemburo wose | NMT 100cfu / g | 87 cfu / g |
| E.Coli | NMT 30cfu / g | 10 cfu / g |
| Salmonella | Ibibi | Ibibi |
| Umwanzuro | Ihuza na Standard Standard | |
Ingaruka nyamukuru za Sinomenine Hydrochloride zirimo:
(1) Kurwanya inflammatory: Kugabanya gucana.
(2) Analgesic: Itanga ububabare.
(3) Immunosuppressive: Guhagarika ibikorwa bya sisitemu yumubiri.
(4) Kurwanya rubagimpande: Kuvura rubagimpande ya rubagimpande.
(5) Neuroprotective: Irinda ingirabuzimafatizo kwangirika.
(6) Kurwanya fibrotic: Irinda cyangwa igabanya fibrosis.
Sinomenine Hydrochloride ikoreshwa cyane cyane mubice bikurikira:
(1) Rheumatology: Kuvura rubagimpande ya rubagimpande.
(2) Gucunga ububabare: Kugabanya ububabare budashira.
(3) Kurwanya inflammatory: Kugabanya umuriro.
(4) Immunomodulation: Guhindura sisitemu yumubiri.
(5) Neuroprotection: Ikoreshwa rishoboka mubuvuzi bwa neuroprotective.
Igikorwa cyo gukora Powder ya Sinomenine Hydrochloride irashobora kuvunagurwa muburyo bukurikira:
Gutegura ibyatsi:Kwoza no kumisha ibikoresho byibiti bibisi.
Gukuramo:Gukoresha umusemburo nka Ethanol kugirango ukure sinomenine mubikoresho byibimera.
Kwibanda:Guhumeka umusemburo kugirango ushimangire ibirimo sinomenine.
Alkalisation:Guhindura pH kugirango uhindure sinomenine muburyo bwumunyu.
Gukuramo Amazi-Amazi:Kweza hamwe na solge organic nka anisole cyangwa 1-heptanol.
Gukaraba:Gukaraba amazi kugirango ukureho umwanda hamwe nibisobanuro bya solvent.
Acide:Kugabanya pH kugusha hydrocloride ya sinomenine.
Crystallisation:Gukora kristu ya sinomenine hydrochloride.
Gutandukana:Centrifuging cyangwa kuyungurura gutandukanya kristu nigisubizo.
Kuma:Kuraho ubuhehere busigaye muri kristu.
Gusya:Gusya kristu yumye mo ifu nziza.
Gukata:Kugenzura ibipimo bimwe bigabanywa.
Kugenzura ubuziranenge:Kwipimisha ubuziranenge, kwibanda, hamwe na mikorobi.
Gupakira:Ibikoresho bitekanye kandi byizewe byo gukwirakwiza.
Ububiko: Bika ahantu hakonje, humye, kandi hasukuye, Kurinda ubushuhe n’umucyo utaziguye.
Igipapuro kinini: 25kg / ingoma.
Igihe cyo kuyobora: iminsi 7 nyuma yo gutumiza.
Ubuzima bwa Shelf: imyaka 2.
Icyitonderwa: Ibisobanuro byihariye nabyo birashobora kugerwaho.
Express
Munsi ya 100kg, Iminsi 3-5
Serivisi ku muryango byoroshye gufata ibicuruzwa
Ku nyanja
Kurenga 300 kg, Hafi Iminsi 30
Icyambu kugeza ku cyambu serivisi yumwuga yemewe arakenewe
Na Air
100kg-1000kg, Iminsi 5-7
Ikibuga cyindege cya serivise yikibuga cyumwuga gikenewe
Bioway Organic yabonye USDA na EU organic, BRC, ISO, HALAL, KOSHER, na HACCP.
